Ectopy-triggering ganglionated plexuses ablation to prevent atrial fibrillation: GANGLIA-AF study.

Background: The ganglionated plexuses (GPs) of the intrinsic cardiac autonomic system may play a role in atrial fibrillation (AF).

Objective: We hypothesized that ablating the ectopy-triggering GPs (ET-GPs) prevents AF.

Methods: GANGLIA-AF (ClinicalTrials.

The ectopy-triggering ganglionated plexuses in atrial fibrillation.

Background: Epicardial ganglionated plexuses (GP) have an important role in the pathogenesis of atrial fibrillation (AF). The relationship between anatomical, histological and functional effects of GP is not well known. We previously described atrioventricular (AV) dissociating GP (AVD-GP) locations.

Comparative analysis of diagnostic 12-lead electrocardiography and 3-dimensional noninvasive mapping.

The clinical utility of noninvasive electrocardiographic imaging has been demonstrated in a variety of conditions. It has recently been shown to have superior predictive accuracy and higher clinical value than validated 12-lead electrogram algorithms in the localization of arrhythmias arising from the ventricular outflow tract, and displays similar potential in other conditions.