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Publications by authors named "Kevin M Gernavage"

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Stem cell delivery of therapies for brain disorders.
Alexander Aleynik Kevin M Gernavage Yasmine Sh Mourad Lauren S Sherman Katherine Liu

Clin Transl Med

August 2014

Article Synopsis
  • The blood-brain barrier (BBB) makes it challenging to deliver drugs effectively for brain cancers and neurodegenerative diseases.
  • Stem cells, particularly neural stem cells (NSCs) and mesenchymal stem cells (MSCs), offer potential as delivery vehicles since they can cross the BBB and target brain tumors like glioblastoma multiforme (GBM).
  • MSCs are considered a safer option than embryonic stem cells, as they do not form tumors and can migrate to areas of injury, making them suitable for clinical trials and potentially available for quick use in treatments.
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