Vivien Thomas: His Legacy and Lessons.

Vivien Thomas was born into humble beginnings in Iberia, Louisiana in 1910. The circumstances of that era prevented him from achieving his goal of attending medical school. He became a surgical research technician at Vanderbilt Medical School.

The Great Masquerader's New Wardrobe in the Modern Era: The Paraneoplastic Manifestations of Renal Cancer.

Paraneoplastic syndromes can occur in 8% to 20% of individuals with malignancies. They can occur in a variety of cancers that include breast, gastric, leukemia, lung, ovarian, pancreatic, prostate, testicular, as well as kidney. The classic presentation of the triad of mass, hematuria, and flank pain occurs in less than 15% of patients with renal cancer.

The Prostate as an Endocrine Organ: Its Modulation of Serum Testosterone.

Aside from nonmelanoma skin cancer, prostate cancer is the most common cancer among men in the United States, and benign prostatic hyperplasia is the most common benign tumor found in men. Until recently, its endocrine functions and possible influence on the hypothalamic-pituitary axis have been relatively understudied. This review summarizes the current understanding of the potential endocrine functions of prostate cancer and benign prostate tissue.

The Inexorable March of Prostate Cancer Research: Testosterone and Beyond.

The history of prostate cancer treatment is filled with progress over the past 120 years. The understanding of the role of testosterone in the genesis of prostate cancer continues to evolve. Diagnostic testing and the treatment of localized and metastatic prostate cancer have undergone major changes over recent decades and have transformed the outlook for patients with prostate cancer.