Publications by authors named "Kevin Kumar Garala"
Article Synopsis
- Colon cancer is a major cause of cancer-related deaths worldwide, and its ability to metastasize complicates treatment options, making multi-drug resistance and chemotherapy side effects significant challenges.
- RNA technology, particularly RNA-based nanoparticles, is being explored as a promising therapeutic intervention for targeted gene silencing and drug delivery in colon cancer treatment, currently under clinical studies.
- Despite the potential of RNA therapies, issues like low stability and cellular uptake exist; however, nanotechnology offers a solution by enhancing RNA delivery to tumor sites while protecting it from degradation and immune responses.
Cancer is defined as the unchecked expansion of aberrant cells. Radiation, chemotherapy, and surgery are currently used in combination to treat cancer. Traditional drug delivery techniques kill healthy proliferating cells when used over prolonged periods of time in cancer chemotherapy.
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