Functional gallbladder disorder: Interim analysis of a prospective cohort study.

Background: Functional gallbladder disorder (FGBD) remains a controversial indication for cholecystectomy.

Methods: A prospective cohort study enrolled patients strictly meeting Rome criteria for FGBD, and cholecystectomy was performed. They were assessed pre- and 3 and 6 months postoperatively with surveys of abdominal pain and quality of life (RAPID and SF-12 surveys, respectively).

Recent advances in pharmacotherapy for epilepsy.

Purpose Of Review: Epilepsy affects 70 million people worldwide and is a significant cause of morbidity and early mortality. The mainstay of therapy is oral medications. Epilepsy drug development is escalating, driven by continued drug resistance in up to a third of epilepsy patients.