PURLs: More isn't better with acute low back pain treatment.

Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects.

Consider this strategy for upper GI bleeds.

Patients with acute upper GI bleed are less likely to experience adverse events--and more likely to survive--when their care is governed by a restrictive transfusion policy.