Publications by authors named "Kevin Douglas"

Mandatory reporting (MR) among service providers (SP) working with intimate partner violence (IPV) is controversial, and the research is scarce. The potential association of SPs experience with IPV and MR-IPV and their attitudes is the aim of the current study. A total of 374 SPs working with victims and perpetrators (help-seekers) of IPV participated in this study.

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Rate coefficients for the reaction of CH with CHO were measured for the first time over the temperature range of 37-603 K, with the CH radicals produced by pulsed laser photolysis and detected by CH radical chemiluminescence following their reaction with O. The low temperature measurements (≤93 K) relevant to the interstellar medium were made within a Laval nozzle gas expansion, while higher temperature measurements (≥308 K) were made within a temperature controlled reaction cell. The rate coefficients display a negative temperature dependence below 300 K, reaching (1.

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  • In a study on palmoplantar psoriasis, risankizumab (RZB) was evaluated against a placebo (PBO) for 16 weeks, followed by an extension to week 52.
  • The results showed that RZB significantly outperformed PBO in achieving clear or nearly clear skin, with various response measures showing marked improvement at week 16.
  • RZB was found to be well-tolerated, with no new safety issues arising throughout the study, though it was noted that there was no comparison with other biologic treatments.
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  • The study investigates how achieving clinical disease control impacts patient-reported outcomes (PROs), especially quality of life (QoL), in individuals with psoriatic arthritis (PsA).
  • It analyzes data from two long-term clinical trials involving patients whose responses to standard treatments were inadequate, highlighting the effectiveness of upadacitinib and adalimumab.
  • Results show that patients reaching minimal disease activity (MDA) or very low disease activity (VLDA) significantly report better QoL and health status compared to those who do not achieve such control, indicating a strong link between clinical improvements and PROs.
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Objective: To identify factors associated with non-treatment with biologic and non-biologic disease modifying anti-rheumatic drugs (DMARDs) during the 12 months after initial inflammatory arthritis (IA) diagnosis.

Methods: We identified Veterans with incident IA diagnosed in 2007-2019. We assessed time to treatment with Kaplan-Meier curves.

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The first experimental study of the low-temperature kinetics of the gas-phase reaction between NH and NO has been performed. A pulsed laser photolysis-laser-induced fluorescence technique was used to create and monitor the temporal decay of NH in the presence of NO. Measurements were carried out over the temperature range of 24-106 K, with the low temperatures achieved using a pulsed Laval nozzle expansion.

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Objectives: Compulsory mental health care includes compulsory hospitalisation and outpatient commitment with medication treatment without consent. Uncertain evidence of the effects of compulsory care contributes to large geographical variations and a controversy on its use. Some argue that compulsion can rarely be justified and should be reduced to an absolute minimum, while others claim compulsion can more frequently be justified.

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In our article, "How much does that cost? Examining the economic costs of crime in North America attributable to people with psychopathic personality disorder" (Gatner et al., 2023, pp. 391-400), we estimated that psychopathic personality disorder (PPD) was associated with substantial crime costs, using a top-down approach of national costs in the United States and Canada.

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The first experimental study of the low-temperature kinetics of the gas-phase reaction of NH with acetaldehyde (CHCHO) has been performed. Experiments were carried out using laser-flash photolysis and laser-induced fluorescence spectroscopy to create and monitor the temporal decay of NH in the presence of CHCHO. Low temperatures relevant to the interstellar medium were achieved using a pulsed Laval nozzle expansion.

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Background: The objective of this post-hoc analysis was to assess the efficacy and safety of upadacitinib in psoriatic arthritis (PsA) patients with axial involvement.

Methods: Post-hoc analysis of SELECT-PsA 1 and SELECT-PsA 2 in patients randomized to upadacitinib 15 mg (UPA15), placebo (switched to UPA15 at week 24), or adalimumab 40 mg (ADA; SELECT-PsA 1 only). Axial involvement was determined by investigator judgement (yes or no; based on the totality of available clinical information, such as duration and characteristics of back pain, age of onset, and previous lab investigations and imaging, if available) alone, or investigator judgement and patient-reported outcome (PRO)-based criteria (Bath Ankylosing Spondylitis Disease Activity Index [BASDAI] ≥ 4 and BASDAI Q2 ≥ 4).

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The current prospective risk assessment study evaluated the application of the Chinese translation of the Historical-Clinical-Risk Management-20 Version 3 (HCR-20 ) in a sample of 152 offenders with mental disorders and civil psychiatric patients. The ratings of the presence and relevance of risk factors were compared, as well as summary risk ratings (SRRs), both across offenders and civil psychiatric patients, and across male and female sub-samples. Interrater reliability was consistently "excellent" for the presence and relevance of risk factors and for SRRs.

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Assessing violence risk amongst forensic patients is a vital legal and clinical task. The field of violence risk assessment has developed considerably over the past two decades but remains primarily risk focused. Despite this, growing attention to and work on protective factors or strengths has occurred.

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Section III of the fifth iteration of the (-5) includes an alternative model of personality disorder diagnosis that conceptualizes antisocial personality disorder as an interpersonal, rather than behavioral, construct. However, the diagnostic specifier for psychopathy has been met with recent controversy due to its conceptual and empirical overlap with triarchic boldness, which has been debated as a necessary and sufficient domain of psychopathy. This study examined the concurrent, convergent, and discriminant validity of the specifier using canonical correlation analysis in samples of undergraduate students ( = 224) and community adults with prior criminal involvement ( = 306).

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  • * In a post hoc analysis of two clinical trials, it was found that a significantly higher percentage of patients treated with upadacitinib 15 mg reached LDA/MDA compared to those on placebo after 24 weeks, and these benefits were maintained at 56 weeks.
  • * The results suggest that treating PsA patients with upadacitinib can help them achieve remission and LDA, making it a viable treatment option.
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The rate constants of many reactions currently considered to be important in the atmospheric chemistry of mercury remain to be measured in the laboratory. Here we report the first experimental determination of the rate constant of the gas-phase reaction between the HgBr radical and ozone, for which a value at room temperature of (HgBr + O) = (7.5 ± 0.

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Cost of illness research has established that mental disorders lead to significant social burden and massive financial costs. A significant gap exists for the economic burden of many personality disorders, including psychopathic personality disorder (PPD). In the current study, we used a top-down prevalence-based cost of illness approach to estimate bounded crime cost estimates of PPD in the United States and Canada.

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Objective: Despite advances in developing structured risk assessment instruments, there is currently no instrument to assess and manage the risk of intimate partner violence perpetration among adolescents. Given the empirical link between many forms of antisocial behavior, we tested whether structured tools commonly used by professionals to evaluate adolescents' risk of engaging in general violence and offending could be used to identify adolescents at risk for perpetrating intimate partner violence.

Hypotheses: Because researchers have not yet examined whether risk assessment tools for general violence and offending predict intimate partner violence perpetration, we did not have a priori hypotheses regarding the predictive validity of these tools for this purpose.

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  • Genetic differences in cerebellar sensitivity to alcohol influence alcohol consumption behaviors in rodents, which may reflect risks for alcohol use disorders in humans.
  • Low alcohol-consuming rodent genotypes, like B6N mice, show enhanced GABAR currents in response to alcohol, while high alcohol-consuming genotypes, like B6J mice, show suppressed currents, linked to nNOS expression.
  • B6N mice consume less alcohol than B6J mice, not due to taste differences, but because of higher nNOS levels leading to increased GABAR activity, illustrating how genetic variation can affect alcohol intake behaviors.
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The Comprehensive Assessment of Psychopathic Personality-Lexical Rating Scale (CAPP-LRS) is a self-report instrument designed to index psychopathy according to the CAPP psychopathy framework. Developed with the expressed goal of advancing the state of knowledge regarding the specific features of psychopathy, the CAPP model and associated instruments have garnered increasing attention and support in the field. Despite the conceptual strength of the CAPP model, the advanced lexical structure of its primary research tool (the CAPP-LRS) has led researchers to question the utility of the instrument for use with some populations of interest (e.

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The Comprehensive Assessment of Psychopathic Personality (CAPP) is a lexically based conceptual model of psychopathy. Despite widespread use in research settings, the Lexical Rating Scale for the CAPP (CAPP-LRS) requires an advanced reading level for completion. The present study is the first to evaluate the content validity of the CAPP-Basic, a lexically simplified version of the CAPP-LRS designed for use with individuals possessing lower verbal skills.

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Reports an error in "Examining the incremental and interactive effects of boldness with meanness and disinhibition within the triarchic model of psychopathy" by Dylan T. Gatner, Kevin S. Douglas and Stephen D.

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The research evidence is very strong for high recidivism rates of violence after discharge from forensic facilities. Big data research has found that a substantial proportion of the forensic population with relapse into violence has a psychosis diagnosis and a criminal record. However, more research on the association between psychotic symptoms and violence may inform and enhance risk assessment, prevention, and treatment.

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