Publications by authors named "Kevin Crow"
Article Synopsis
- Atherosclerosis affects the homeostasis of T regulatory cells (Tregs) by promoting their plasticity, leading to a decrease in CXCR3 Tregs and an increase in a dysfunctional Th1-like Treg subset.
- Research in Apoe mice revealed that these Th1/Tregs, which derive from genuine Tregs instead of T-effector cells, show impaired functionality in suppressing inflammation.
- The study highlights that atherosclerosis enhances Treg plasticity through specific pathways, contributing to arterial inflammation and the progression of atherosclerosis.
