Investigations on the Degradation of the Bile Salt Cholate via the 9,10--Pathway Reveals the Formation of a Novel Recalcitrant Steroid Compound by a Side Reaction in sp. Strain Chol11.

Bile salts such as cholate are steroid compounds from the digestive tracts of vertebrates, which enter the environment upon excretion, e.g., in manure.

A Novel Steroid-Coenzyme A Ligase from Novosphingobium sp. Strain Chol11 Is Essential for an Alternative Degradation Pathway for Bile Salts.

Bile salts such as cholate are steroid compounds with a C carboxylic side chain and occur ubiquitously in vertebrates. Upon their excretion into soils and waters, bile salts can serve as growth substrates for diverse bacteria. sp.