Publications by authors named "Kevin C Shilling"
Background: Adaptive servoventilation (ASV) can be effective therapy for specific types of central apnea such as Cheyne-Stokes respiration (CSR). Patients treated chronically with opioids develop central apneas and ataxic breathing patterns (Biot's respiration), but therapy with CPAP is usually unsuccessful. There are no published studies of ASV in patients with sleep apnea complicated by chronic opioid therapy.
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- Chronic opioid therapy has surged for pain management, yet its impact on sleep-related breathing has been insufficiently studied.
- A study compared the sleep breathing patterns of 60 chronic opioid users to 60 non-users, finding higher apnea rates and lower oxygen saturation in the opioid group.
- Results indicated a dose-dependent relationship where higher morphine doses correlated with more severe breathing issues during sleep, including central apneas and irregular breathing patterns.
Background: Sleep-disordered breathing and hypoxemia frequently underlie many common medical conditions for which patients require hospitalization. Sleep apnea is associated with adverse cardiovascular, neurovascular, inflammatory, and metabolic consequences, many of which can be reversed with nasal continuous positive airway pressure. Although polysomnography is the gold standard for outpatient evaluation of sleep apnea, it has not been used for establishing the diagnosis or as a means to intervene with evidence-based therapy in the hospital setting.
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