Publications by authors named "Kevin Barraclough"

Background: The aim was to characterise the sociodemographic, general health and polymyalgia rheumatica (PMR)-specific features of participants in a large inception cohort of patients with PMR diagnosed in UK primary care.

Methods: Patients (n = 739) with a new diagnosis of PMR were referred into the study and mailed a questionnaire detailing their general health and sociodemographic characteristics in addition to the symptoms of and treatment for PMR. Characteristics of responders and non-responders were compared and descriptive statistics were used to characterise the health of the cohort.

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Objectives: To estimate data loss and bias in studies of Clinical Practice Research Datalink (CPRD) data that restrict analyses to Read codes, omitting anything recorded as text.

Design: Matched case-control study.

Setting: Patients contributing data to the CPRD.

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Article Synopsis
  • The paper talks about guidelines for treating polymyalgia rheumatica (PMR), a type of illness that causes pain and stiffness, which are not consistent worldwide.
  • It describes recommendations made in 2015 by two important groups, EULAR and ACR, based on thorough research and expert opinions on how to manage PMR.
  • The guidelines include advice on medical tests, treatments like glucocorticoids, and when to refer patients to specialists, helping doctors provide the best care for PMR patients.
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Article Synopsis
  • There are no global guidelines yet for treating polymyalgia rheumatica (PMR), which makes treatment different in various places.
  • This paper shares recommendations from a 2015 meeting by experts in Europe and America to help doctors manage PMR better.
  • They created eight main principles and nine specific tips that cover patient care, types of treatments, and recommendations for doctors to follow to help patients with PMR.
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Article Synopsis
  • - The study aimed to assess the relationship between non-visible haematuria and the risk of bladder cancer, highlighting that non-visible haematuria has not been thoroughly evaluated previously.
  • - Using data from UK primary care medical records, the research involved 4,915 bladder cancer patients and 21,718 matched controls, finding a significant association between non-visible haematuria and increased cancer risk (odds ratio of 20).
  • - Although both types of haematuria are linked to bladder cancer, visible haematuria shows nearly double the risk compared to non-visible, suggesting visible symptoms should be prioritized in screening practices by general practitioners.
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Background: Polymyalgia Rheumatica (PMR) is the commonest inflammatory condition seen in older patients in primary care. To date, however, research has been focused on secondary care cohorts rather than primary care where many patients are exclusively managed. This two year prospective inception cohort study of PMR patients will enable us to understand the full spectrum of this condition.

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