Publications by authors named "Ketki Jawade"
Indian J Pediatr
July 2024
Article Synopsis
- * CVA6 was notably linked to an atypical rash that spread beyond typical locations like hands and mouth, affecting areas like the face and trunk, while co-infections and recurrent cases were also observed.
- * Molecular analysis categorized CVA6 as group D3 and CVA16 as group B1c, emphasizing the importance of monitoring changes in the clinical features of enteroviruses associated with HFMD.
Article Synopsis
- Biosimilars are replicas of original biopharmaceuticals and hold a major share in this industry, particularly exemplified by Adalimumab (Humira), a monoclonal antibody that effectively blocks TNF-α with low immunogenicity.
- To address the challenges of cost-effective monoclonal antibody development, researchers created a stable CHO-K1 cell line to produce a new biosimilar called H9P2S against TNF-α.
- Functional assays demonstrated that H9P2S exhibits comparable TNF-α binding and neutralizing properties to Adalimumab, suggesting it is a viable option for biosimilar drug development.
Int J Infect Dis
May 2021
Article Synopsis
- India has a significant burden of SARS-CoV-2 infection, with various RT-PCR detection methods leading to potential reporting delays and management issues.
- A new Viroselect RT-PCR assay was developed targeting a specific region in the virus's ORF1a gene, demonstrating high concordance with existing diagnostic tests.
- In tests of 701 samples, Viroselect showed an agreement of up to 87.6% with manual assays and successfully resolved inconclusive results in nearly all cases evaluated, indicating its promise for improved diagnostic reliability.
