Dicoumarol complexes of Cu(II) based on 1,10-phenanthroline: synthesis, X-ray diffraction studies, thermal behavior and biological evaluation.

A series of Cu(II) complexes containing dicoumarol derivatives and 1, 10-phenanthroline have been synthesized. Structural and spectroscopic properties of ligands were studied on the basis of mass spectra, NMR ((1)H and (13)C) spectra, FT-IR spectrophotometry and elemental analysis, while physico-chemical, spectroscopic and thermal properties of mixed ligand complexes have been studied on the basis of infrared spectra, mass spectra, electronic spectra, powder X-ray diffraction, elemental analysis and thermogravimetric analysis. X-ray diffraction study suggested the suitable octahedral geometry for hexa-coordinated state.

Multiple heating rate kinetic parameters, thermal, X-ray diffraction studies of newly synthesized octahedral copper complexes based on bromo-coumarins along with their antioxidant, anti-tubercular and antimicrobial activity evaluation.

Series of new Cu(II) complexes were synthesized by classical thermal technique. The biologically potent ligands (L) were prepared by refluxing 6-brom 3-acetyl coumarin with aldehydes in the presence of piperidine in ethanol. The Cu(II) complexes have been synthesized by mixing an aqueous solution of Cu(NO(3))(2) in 1:1 molar ratios with ethanolic bidentate ligands and Clioquinol.

Prevalence of alternative splicing choices in Arabidopsis thaliana.

Background: Around 14% of protein-coding genes of Arabidopsis thaliana genes from the TAIR9 genome release are annotated as producing multiple transcript variants through alternative splicing. However, for most alternatively spliced genes in Arabidopsis, the relative expression level of individual splicing variants is unknown.

Results: We investigated prevalence of alternative splicing (AS) events in Arabidopsis thaliana using ESTs.

Oral contraceptives for inducing ovulation delay in orthodox Jewish women: a report of 2 cases.

Background: Orthodox Jewish women are prohibited from participating in sexual intercourse from the start of menstruation to 7 days after the end of flow, when they participate in a ritual bath.

Case: Two orthodox Jews with ovulation prior to initiating sexual intercourse were treated with oral contraceptives to delay ovulation.

Conclusion: Oral contraceptive treatment strategies are effective at delaying ovulation until after the ritual cleansing for orthodox Jewish women with short follicular phases.

Luteinizing hormone secretion is not influenced by insulin infusion in women with polycystic ovary syndrome despite improved insulin sensitivity during pioglitazone treatment.

It has been reported in women with polycystic ovary syndrome (PCOS) that LH secretion is not altered by insulin infusion. To determine whether insulin resistance may have precluded an effect of insulin, pulsatile LH secretion and gonadotropin responses to GnRH were examined in PCOS women (n = 9) before and after pioglitazone treatment (45 mg/d) for 20 wk in the presence and absence of a hyperinsulinemic euglycemic clamp (80 mU/m2.min).

Initial evaluation and management of infertility by the primary care physician.

Infertility is a common condition seen in primary care practices. Infertility is defined as 1 year of unprotected intercourse during which a pregnancy is not achieved. in the United States, 15% to 20% of all couples are infertile, with higher rates seen in older couples.