Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock.

Objective: The objectives of this study were to determine myocardial injury in patients with septic shock by measuring serum cardiac troponin I (cTnI), to evaluate relationship between elevated cTnI and myocardial dysfunction and to determine if cTnI is a predictor of outcome in these patients.

Methods: Thirty-seven consecutive patients with septic shock were included in the study. Serum cTnI was measured at study entry and after 24 and 48 h.

Clinical usefulness and prognostic value of elevated cardiac troponin I levels in acute pulmonary embolism.

Background: Right ventricular myocardial ischemia and injury contribute to right ventricular dysfunction and failure during acute pulmonary embolism. The objective of this study was to evaluate the clinical usefulness of cardiac troponin I (cTnI) in the assessment of right ventricular involvement and short-term prognosis in acute pulmonary embolism

Methods: Thirty-eight patients with acute pulmonary embolism were included in the study. Clinical characteristics, right ventricular involvement, and clinical outcome were compared in patients with elevated levels of serum cTnI versus patients with normal levels of serum cTnI.

Pneumocystis carinii pneumonia presenting as a fever of unknown origin in a patient without AIDS.

Pneumocystis Carinii pneumonia (PCP) remains an opportunistic infection that causes substantial morbidity and mortality in patients who have impaired immune function. PCP in patients who do not have AIDS usually manifests in a more fulminant manner than in patients with AIDS. In recent years, PCP has been reported increasingly in patients with connective tissue disorders.