Comparative evaluation of various biomaterials as pulpotomy agents in molars with symptomatic irreversible pulpitis: A randomized single-blinded single-center control trial.

Introduction: Untreated tooth decay in mature permanent dentition is a prevalent global issue, affecting 34.1% of people with 2.5 billion cases annually.

A Comparative Evaluation of Fracture Resistance of Endodontically Treated Teeth Using Different Post-Obturation Restorative Materials: An Study.

Unlabelled: This study was conducted to evaluate and compare the fracture resistance of endodontically treated teeth using different post-obturation restorative materials. Seventy-five non-carious extracted human teeth were collected. Access opening, chemicomechanical preparation, and obturation were done.

A Rare Complication of Maxillary Third Molar Extraction.

The removal of tuberosity post extraction of the maxillary third molar is a very rare complication and there has not been ample discussion in the literature. Forceful extraction of a maxillary third molar can lead to soft and hard tissue loss. Various techniques have been used for the management of such defects such as local flaps, free soft tissue flaps, free bone flaps, and even tissue engineering.

Open Apex and its Management: Review Article.

During root development, the teeth are subjected to a variety of assaults. Due to this, the root stops forming and the closure of the apex does not take place. Root canal treatment becomes a major challenge in these cases because of the width of the canal and wide-open apices.

A Light Microscopic Study Comparing Pulp Histological Alterations Following Tooth Preparation Using a High-speed Handpiece and an Er: YAG Laser.

Introduction: Histological alterations were evaluated in this study after tooth preparation with carbide burs using a traditional handpiece and Er: YAG laser.

Methods: Tooth preparation was done on 30 intact maxillary first premolars of healthy patients. Ten maxillary first premolars were used as control, wherein no tooth preparation was done.

A comparative evaluation of remaining dentin thickness following biomechanical preparation of teeth using different rotary file systems: An study.

Aim: The aim of the study is to compare and evaluate the remaining dentin thickness following biomechanical preparation of teeth using different rotary file systems.

Materials And Methodology: Sixty noncarious mandibular premolar teeth were collected and decoronated at the level of cementoenamel junction with a diamond disc. All specimens were randomly divided into 5 experimental groups - ProTaper Next (Dentsply Mallifer), Mtwo (VDW, Antaeus, Munich, Germany), RaCe (FKG, La Chaux-de-Fonds, Switzerland), Hyflex electro-discharge machining (EDM) (Coltene-Whaledent, Allstetten, Switzerland), NeoNiTi (Neolix, France) and 1 control group of 10 teeth each.

Antigen-Based Point of Care Testing (POCT) for Diagnosing SARS-CoV-2: Assessing Performance.

Currently, the most accurate way to diagnose an active SARS-CoV-2 (COVID-19) infection is through detection of viral RNA using reverse transcription polymerase chain reaction (RT-PCR) test. While RT-PCR tests are the most sensitive for identifying infection, there are significant limitations, such as global access to sufficient test kits, turnaround times (TAT) from specimen collection to test result is often greater than 24 h and the need for skilled operators in accredited laboratories requiring specialized equipment. A rapid test performed at the point of care (POC) could provide a result within an approximate time of 30 min post specimen collection, be performed by a health care worker and comprise a simple workflow, improving both turnaround time and potentially decreasing costs (e.

Thrombospondin 1 polymorphism associated with decreased expression and increased risk of pterygium.

Purpose: To assess the potential association of a thrombospondin 1 gene (THBS1) single-nucleotide polymorphism (rs1478604) with thrombospondin 1 (TSP-1) mRNA expression, as well as the risk of pterygium, in a pilot study.

Methods: DNA and RNA were isolated from peripheral blood samples collected from normal volunteer subjects (n = 39). In addition, DNA was isolated from conjunctival tissue samples collected during pterygium excision surgeries (n = 42).

Astigmatism Management with Intraocular Lens Surgery.

Corneal astigmatism is common. More than 40% of patients undergoing cataract surgery have 1 diopter (D) power or more of astigmatism, which left untreated is visually significant. Because toric intraocular lenses (IOLs) are available, the current standard of care is to offer treatment of astigmatism at the time of cataract surgery.

Recombinant Fusion Protein PbrD Cross-Linked to Calcium Alginate Nanoparticles for Pb Remediation.

Lead (Pb) pollution arising from industrial and mining activities has led to widespread environmental toxicity, particularly in South Africa. Humans exposed to Pb are reported to suffer from detrimental health impacts that can lead to fatalities. As such, there is an urgent need to remediate Pb from the environment.

Recombinant expression and purification of a functional bacterial metallo-chaperone PbrD-fusion construct as a potential biosorbent for Pb(II).

PbrD is a lead (II) binding protein encoded by the pbr lead resistance operon found exclusively in Cupriavidus metallidurans CH34. Its ability to sequester Pb(II) shows potential for it to be developed as a biosorbent for Pb in the bioremediation of contaminated wastewaters. In this study the pbrD gene from C.

Local inhibition of 5-lipoxygenase enhances bone formation in a rat model.

Objectives: Recent studies have shown that modulating inflammation-related lipid signalling after a bone fracture can accelerate healing in animal models. Specifically, decreasing 5-lipoxygenase (5-LO) activity during fracture healing increases cyclooxygenase-2 (COX-2) expression in the fracture callus, accelerates chondrogenesis and decreases healing time. In this study, we test the hypothesis that 5-LO inhibition will increase direct osteogenesis.

Prevalence of spaced and closed dentition and its relation to malocclusion in primary and permanent dentition.

An ideal primary dentition is the indicator of future ideal permanent dentition. Absence of primate or secondary spaces in the primary dentition is expression of disproportion between jaw/tooth sizes. Little information is known on the relationship of spacing and closed dentition with malocclusion in relation to primary and permanent dentition.

Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts.

Tissue engineering is an alternative approach for the preparation of small-diameter (<6mm) vascular grafts due to the potential to control thrombosis, anastomotic cellular hyperplasia and matrix production. This control also requires the maintenance of graft patency in vivo, appropriate mechanical properties and the formation of a functional endothelium. As a first step in generating such tissue-engineered vascular grafts (TEVGs), our objective was to develop a tissue-engineered construct that mimicked the structure of blood vessels using tubular electrospun silk fibroin scaffolds (ESFSs) with suitable mechanical properties.