Solid-liquid interface charge transfer for generation of HO and energy.

Solid-liquid contact electrification is a widespread interface phenomenon in nature. Recent research and theory demonstrate that electron transfer during this process holds the potential to initiate interfacial chemical reactions. Here, we design a dual-functional device for generation of HO and energy.

Emerging advances in drug delivery systems (DDSs) for optimizing cancer complications.

The management and treatment of tumor complications pose continuous challenges due to the inherent complexity. However, the advent of drug delivery systems (DDSs) brings promising opportunities to address the tumor complications using innovative technological approaches. This review focuses on common oncological complications, including cancer thrombosis, malignant serous effusion, tumor-associated infections, cancer pain, and treatment-related complications.

Air-Processed Efficient Perovskite Solar Cells With Full Lifecycle Management.

Despite the outstanding power conversion efficiency of perovskite solar cells (PSCs) realized over the years, the entire lifecycle from preparation and operation to discarding of PSCs still needs to be carefully considered when it faces the upcoming large-scale production and deployment. In this study, bio-derived chitin-based polymers are employed to realize the full lifecycle regulation of air-processed PSCs by forming multiple coordinated and hydrogen bonds to stabilize the lead iodide and organic salt precursor inks, accelerating the solid-liquid reaction and crystallization of two-step deposition process, then achieving the high crystalline and oriented perovskites with less notorious charge defects in the open air. The air-prepared PSCs exhibit a decent efficiency of 25.

Facilitating Charge Transfer via Ti-Knot Pathway in Electrochromic Three-Dimensional Metalated Covalent Organic Frameworks.

Due to the ordered one-dimensional channel as well as accessible redox sites, two-dimensional covalent organic frameworks (2D COFs) have garnered extensive attention in the field of electrochromism. However, organic 2D frameworks impose limitations on charge transfer and the weak interlayer interactions in 2D COFs, adversely affecting the stability during switching processes. Herein, we introduced Ti knots to construct three-dimensional metalated covalent organic frameworks (3D MCOFs), denoted as Ti-DHTA-Py.

A selective frequency damping and Janus adhesive hydrogel as bioelectronic interfaces for clinical trials.

Maintaining stillness is essential for accurate bioelectrical signal acquisition, but dynamic noise from breathing remains unavoidable. Isotropic adhesives are often used as bioelectronic interfaces to ensure signal fidelity, but they can leave irreversible residues, compromising device accuracy. We propose a hydrogel with selective frequency damping and asymmetric adhesion as a bioelectronic interface.

Ultralong Bistable, Electrolytic MnO-Based, Electrochromic Battery Enabled by Porous, Low-Barrier, Hydroxylated TiO Interface.

Electrochromic (EC) battery technology shows great potential in future "zero-energy building" by controlling outdoor solar transmission to tune heat gain as well as storing the consumed energy to reuse across other building systems. However, challenges still exist in exploring an electrochemical system to satisfy requirements on both ultra-long optical memory (also called bistability) without continuous power supply and high energy density. Herein, an EC battery is proposed to demonstrate ultra-long bistability (>760 h) based on the reversible deposition and dissolution of manganese oxide (MnO) without the addition of any mediators.

Scale-Bridging Mechanics Transfer Enables Ultrabright Mechanoluminescent Fiber Electronics.

Mechanoluminescent (ML) fibers and textiles enable stress visualization without auxiliary power, showing great potential in wearable electronics, machine vision, and human-computer interaction. However, traditional ML devices suffer from inefficient stress transfer in soft-rigid material systems, leading to low luminescence brightness and short cycle life. Here, we propose a tendon-inspired scale-bridging mechanics transfer mechanism for ML composites, which employs molecular-scale copolymerized cross-linking and nanoscale inorganic nanoparticles as hierarchical stress transfer sites.

CoFe hydroxide towards CoP-FeP heterojunction for efficient and long-term stable water oxidation.

Electrochemical water splitting stands out as a promising avenue for green hydrogen production, yet its efficiency is fundamentally governed by the oxygen evolution reaction (OER). In this work, we investigated the growth mechanism of CoFe hydroxide formed by in situ self-corrosion of iron foam for the first time and the significant influence of dissolved oxygen in the immersion solution on this process. Based on this, the CoP-FeP/IF heterostructure catalytic electrode demonstrates exceptional OER activity in a 1 M KOH electrolyte, with an overpotential of only 253 ± 4 mV (@10 mA cm), along with durability exceeding 1000 h.

Dual-Function Wearable Hydrogel Optical Fiber for Monitoring Posture and Sweat pH.

In recent years, wearable devices have been widely used for human health monitoring. Such monitoring predominantly relies on the principles of optics and electronics. However, electronic detection is susceptible to electromagnetic interference, and traditional optical fiber detection is limited in functionality and unable to simultaneously detect both physical and chemical signals.

Triboelectric micro-flexure-sensitive fiber electronics.

Developing fiber electronics presents a practical approach for establishing multi-node distributed networks within the human body, particularly concerning triboelectric fibers. However, realizing fiber electronics for monitoring micro-physiological activities remains challenging due to the intrinsic variability and subtle amplitude of physiological signals, which differ among individuals and scenarios. Here, we propose a technical approach based on a dynamic stability model of sheath-core fibers, integrating a micro-flexure-sensitive fiber enabled by nanofiber buckling and an ion conduction mechanism.

Crosstalk between innate immunity and rumen-fecal microbiota under the cold stress in goats.

The balance of the microbiome, which is sensitive to temperature changes, plays a crucial role in maintaining overall health and reducing the risk of diseases. However, the specific mechanisms by which immunity and microbiota interact to adapt to cold stress have yet to be addressed. In this study, Nanjiang Yellow goats were chosen as a model and sampled during the cold (winter, cold stress) and warm (spring) seasons, respectively.

Topological MXene Network Enabled Mixed Ion-Electron Conductive Hydrogel Bioelectronics.

Mixed ion-electron conductive (MIEC) bioelectronics has emerged as a state-of-the-art type of bioelectronics for bioelectrical signal monitoring. However, existing MIEC bioelectronics is limited by delamination and transmission defects in bioelectrical signals. Herein, a topological MXene network enhanced MIEC hydrogel bioelectronics that simultaneously exhibits both electrical and mechanical property enhancement while maintaining adhesion and biocompatibility, providing an ideal MIEC bioelectronics for electrophysiological signal monitoring, is introduced.

Phyto-inspired sustainable and high-performance fabric generators via moisture absorption-evaporation cycles.

Collecting energy from the ubiquitous water cycle has emerged as a promising technology for power generation. Here, we have developed a sustainable moisture absorption-evaporation cycling fabric (Mac-fabric). On the basis of the cycling unidirectional moisture conduction in the fabric and charge separation induced by the negative charge channel, sustainable constant voltage power generation can be achieved.

Circulating tumor DNA: current implementation issues and future challenges for clinical utility.

Over the past decades, liquid biopsy, especially circulating tumor DNA (ctDNA), has received tremendous attention as a noninvasive detection approach for clinical applications, including early diagnosis of cancer and relapse, real-time therapeutic efficacy monitoring, potential target selection and investigation of drug resistance mechanisms. In recent years, the application of next-generation sequencing technology combined with AI technology has significantly improved the accuracy and sensitivity of liquid biopsy, enhancing its potential in solid tumors. However, the increasing integration of such promising tests to improve therapy decision making by oncologists still has complexities and challenges.

Significant CircRNAs in liver cancer stem cell exosomes: mediator of malignant propagation in liver cancer?

Hepatocellular carcinoma (HCC), one of the most prevalent forms of cancer worldwide, presents a significant global healthcare challenge. Cancer stem cells (CSCs), which can influence neighboring non-CSCs, are believed to play a crucial role in tumor growth and resistance to treatment, but the specific mechanisms and mediators are not fully understood. Regulation of the CSC state is considered an ideal therapeutic strategy both in the early stages of tumor formation and within established tumors.

Air-Working Electrochromic Artificial Muscles.

Artificial muscles are indispensable components for next-generation robotics to mimic the sophisticated movements of living systems and provide higher output energies when compared with real muscles. However, artificial muscles actuated by electrochemical ion injection have problems with single actuation properties and difficulties in stable operation in air. Here, air-working electrochromic artificial muscles (EAMs) with both color-changing and actuation functions are reported, which are constructed based on vanadium pentoxide nanowires and carbon tube yarn.

Hyperstable Eutectic Core-Spun Fiber Enabled Wearable Energy Harvesting and Personal Thermal Management Fabric.

Electronic textiles have gradually evolved into one of the most important mainstays of flexible electronics owing to their good wearability. However, textile multifunctionality is generally achieved by stacking functional modules, which is not conducive to wearability. Integrating these modules into a single fiber provides a better solution.

Hierarchical Fermat helix-structured electrochemical sensing fibers enable sweat capture and multi-biomarker monitoring.

Wearable electrochemical sensors have shown potential for personal health monitoring due to their ability to detect biofluids non-invasively at the molecular level. Smart fibers with high flexibility and comfort are currently ideal for fabricating electrochemical sensors, but little research has focused on fluid transport at the human-machine interface, which is of great significance for continuous and stable monitoring and skin comfort. Here, we report an electrochemical sensing fiber with a special core-sheath structure, whose outer layer is wound by nanofibers with a hierarchical Fermat helix structure which has excellent moisture conductivity, and the inner layer is based on CNT fibers covered by three-dimensional reduced graphene oxide folds which have good sensing properties after modification of active materials such as enzymes and selective membranes.

HLF promotes ovarian cancer progression and chemoresistance via regulating Hippo signaling pathway.

Hepatic leukemia factor (HLF) is aberrantly expressed in human malignancies. However, the role of HLF in the regulation of ovarian cancer (OC) remains unknown. Herein, we reported that HLF expression was upregulated in OC tissues and ovarian cancer stem cells (CSCs).

In situ detection of human glioma based on tissue optical properties using diffuse reflectance spectroscopy.

Safely maximizing brain cancer removal without injuring adjacent healthy tissue is crucial for optimal treatment outcomes. However, it is challenging to distinguish cancer from noncancer intraoperatively. This study aimed to explore the feasibility of diffuse reflectance spectroscopy (DRS) as a label-free and real-time detection technology for discrimination between brain cancer and noncancer tissues.