Publications by authors named "Kerstin Melanie Widmann"
Purpose: The efficacy of the novel SphinKeeper® procedure for the treatment of fecal incontinence (FI) is not yet well defined. This study aimed to assess long-term functional outcomes after SphinKeeper® surgery.
Methods: We included 32 patients with FI (28 female), who were operated at a tertiary referral center between August 2018 and September 2021.
Article Synopsis
- A study was conducted in Austria to evaluate the effectiveness of mesenchymal stem cells (specifically Cx601-darvadstrocel) in treating complex anal fistulas in patients with perianal fistulizing Crohn's disease.
- Fourteen patients (3 males, 11 females) participated, receiving 120 million stem cells via injection, with success defined as closure of the fistula opening without leakage.
- Results showed a 57.1% success rate for fistula closure after a median follow-up of 92 weeks, but the overall improvement in disease activity was not statistically significant.
The Sphinkeeper procedure for treating faecal incontinence (FI) may be associated with potential implant migration (IM) and dislocation (ID), with considerable variations regarding their occurrence and effects on consecutive functional outcome. This study assessed IM and ID following the Sphinkeeper procedure and its correlation with physical activity. This was a prospective observational clinical study of ten patients undergoing Sphinkeeper operation due to FI between August 2020 and November 2020 at the Medical University of Vienna.
View Article and Find Full Text PDF(1) Background: The Sphinkeeper implantation for faecal incontinence (FI) is a novel surgical procedure with limited data on its clinical efficacy. Therefore, we aimed to assess the functional outcome following Sphinkeeper surgery in patients with refractory FI. (2) Methods: Between 2018 and 2020, eleven consecutive patients (9 female) with FI met the inclusion criteria and were enrolled for surgery.
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