Derived and displayed power consumption, flow, and pulsatility over a range of HeartMate II left ventricular assist device settings.

Continuous-flow left ventricular assist devices/systems (LVADs/LVASs) reduce symptoms and mortality in severe heart failure. The impeller or centrifugal designs provide challenges in assessing and titrating pump speed (revolutions per minute [RPM]), flow, and native heart pulsatility, and contribution to cardiac output. The Thoratec HeartMate II (HM II) LVAS is the most commonly used LVAD worldwide.

Dissociated expression of Bcl-2 and Ki-67 in endometrial lesions: diagnostic and histogenetic implications.

The objective of the present study was to analyze the expression of the proliferation marker, Ki-67, and the anti-apoptotic protein, bcl-2, in various endometrial lesions. Ki-67 and bcl-2 expressions were studied in 194 specimens of endometrial hyperplasia, polyps, carcinomas, and cyclic endometrium from a defined geographic area. Results were statistically analyzed with respect to marker expression, localization to the stromal or glandular component, and intraglandular topography.