GLP-1 and appetite responses to a meal in lean and overweight adolescents following exercise.

Objective: Increased physical activity is an integral part of weight loss programs in adolescents. We prospectively investigated the effects of exercise on glucagon-like peptide-1 (GLP-1) concentrations and on appetite markers.

Methods And Procedures: Normal weight (NW) and at risk of overweight/overweight (OW) male adolescents (n = 17/gr) underwent five consecutive days of aerobic exercise (1 h/day).

Regulation of appetite in lean and obese adolescents after exercise: role of acylated and desacyl ghrelin.

Context: Increased physical activity is an integral part of weight loss programs in adolescents. We hypothesized that exercise could affect appetite-regulating hormones and the subjective desire to eat, which could partly explain the poor success rate of the existing interventions.

Objective: The objective of this study was to investigate prospectively the effects of exercise on acylated ghrelin (AG) and desacyl ghrelin (DG) concentrations and on appetite.

Application of magnetic resonance imaging to evaluation of femoral neck structure in growing girls.

Conventional density measures by dual-energy X-ray absorptiometry (DXA) are confounded by increases in bone size and do not assess bone geometry. We assessed precision of magnetic resonance imaging (MRI) and used MRI, DXA, and hip structure analysis (HSA) to assess 7-mo changes in bone structure at the femoral neck in 18 prepubertal girls. At baseline, girls were 10.

Bone mass and structure are enhanced following a 2-year randomized controlled trial of exercise in prepubertal boys.

Exercise during growth has a positive influence on bone mineral accrual, yet little is known about how bone geometry and strength adapt to loading during growth. Our primary objective was to compare changes in proximal femur bone geometry and strength between 31 prepubertal (Tanner Stage 1) boys who participated in a school-based, high-impact circuit intervention (12 min, three times a week) for 20 months and 33 maturity-matched controls. Our secondary objective was to compare changes in total body (TB), proximal femur (PF), and lumbar spine (LS) bone mineral content (BMC) and bone area (BA) in these groups.

A school-based exercise intervention elicits substantial bone health benefits: a 2-year randomized controlled trial in girls.

Objective: Childhood weight-bearing physical activity is recognized as an important determinant of peak bone mass, and physical activity intervention may represent a feasible strategy for primary prevention of osteoporosis. Previous school-based exercise interventions have all been of <10 months in duration. We implemented a high-impact, circuit-based, jumping intervention (10 minutes, 3 times a week) over 2 school years and compared changes in bone mineral content (BMC) over 20 months (2 school years) in 9.