The eAutopsy: an effective virtual tool for exposing medical students to the postmortem examination.

Objectives: One reason for declining autopsy numbers is clinicians' lack of familiarity with the practice. We developed an online tool used in place of attending postmortem examinations and aimed to determine if the experience was as effective in affecting medical students' attitudes toward the procedure.

Methods: The eAutopsy was a part of a unit consisting of a mixture of a didactic lecture, readings, and online discussion board.

Malacoplakia of the cranium and cerebrum in a human immunodeficiency virus-infected man. Case report.

Malacoplakia is a rare chronic inflammatory disease associated with infection and immunosuppression, and very few occurrences have been reported in the cerebrum. The authors describe the case of a 41-year-old man with advanced human immunodeficiency virus (HIV) infection who presented with a very aggressive malacoplakia lesion that had extended through the scalp, temporalis muscle, skull bone, and deep through the dura mater into the superior sagittal sinus and adjacent brain. Pathological examination revealed sheets of histiocytes invading these structures, and macrophages containing numerous round bodies known as Michaelis-Guttmann bodies, pathognomic for malacoplakia.

Embryonal rhabdomyosarcoma (sarcoma botryoides) of the cervix presenting as a cervical polyp treated with fertility-sparing surgery and adjuvant chemotherapy.

Background: Embryonal rhabdomyosarcoma (sarcoma botryoides) of the female genital tract is rare in the cervix. It tends to occur in children and young women, and appears to have a better prognosis than sarcoma botryoides of the vagina and uterus.

Case: We report a case of embryonal rhabdomyosarcoma (sarcoma botryoides) presenting as a cervical polyp in a 19-year-old female.

Translocation (2;11)(q31;q12) is recurrent in collagenous fibroma (desmoplastic fibroblastoma).

Collagenous fibroma (desmoplastic fibroblastoma) is a rare, benign tumor composed of spindle and stellate-shaped fibroblasts and myofibroblasts in a densely collagenous background. A t(2;11)(q31;q12) has been reported in one case of collagenous fibroma and a rearrangement of the 11q12 breakpoint in a second case. In the present study, we detected a t(2;11) identical to that previously described in a collagenous fibroma arising in the supraclavicular fossa of a 55-year-old man.

Endometrial adenocarcinoma within a single horn of a didelphic uterus: a report of 2 cases.

Background: Didelphic uterus results from incomplete fusion of the müllerian ducts.

Cases: In 2 cases, endometrial adenocarcinoma arose in 1 horn of a didelphic uterus.

Conclusion: Clinicians should be aware of müllerian anomalies, which may go undetected, resulting in diagnostic delay.