Anti-inflammatory Effect of Ozone Therapy in an Experimental Model of Rheumatoid Arthritis.

To verify the influence of ozone (O) therapy on an experimental model of rheumatoid arthritis (RA), 30 male Wistar rats were randomly allocated to 2 groups, control (C) and treatment (T), and subdivided into control (C12, C48, C72) and treatment (T12, T48, T72) groups. RA was induced by administration of collagenase plus complete Freud's adjuvant in the knee joint region. The animals were treated with ozone therapy (1 ml O injection in the knee i.

Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression.

Transcranial photobiomodulation is an innovative method for the stimulation of neural activity which consists of the exposure of neural tissue to low-level light irradiance. In the present study, light-emitting diodes (LEDs) were used as light source due to their practicality and low cost. The objective was to analyze the effects of transcranial photobiomodulation using 945-nm LED in university students with anxiety and depression.

Study of the Effects of L-tryptophane Nanoparticles on Motor Behavior in Alzheimer's Experimental Models.

Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by the progressive and incapacitating decay of cognitive, neuropsychiatric, and behavioral manifestations. L-tryptophan is the precursor amino acid of serotonin, which is a neurotransmitter responsible for mood balance and the sense of well-being and can be administered in the form of nanoparticles.

Objective: This study analyzed the effectiveness of L-tryptophan nanoparticles and L-tryptophan on behavioral physiological alterations resulting from AD in animal models.

Formulation, characterization, and in vitro/in vivo studies of capsaicin-loaded albumin nanoparticles.

Capsaicin (CAP) is a secondary metabolite with high therapeutic potential. It displays several bioactive properties including hypolipidemic, antioxidant, anti-inflammatory and analgesic effects. However, CAP presents toxicity to healthy cells and poor pharmacokinetic profile, which is characterized by toxic metabolites and short half-life.

Transcranial LED therapy on amyloid-β toxin 25-35 in the hippocampal region of rats.

Excessive Aβ deposition in the brain is associated with the formation of senile plaques, and their diffuse distribution is related to Alzheimer's disease. Thirty rats (EG) were irradiated with light-emitting diode (photobiomodulation (PBM)) in the frontal region of the skull after being inoculated with the Aβ toxin in the hippocampus; 30 rats were used as the control group (CG). The analysis was conducted at 7, 14, and 21 days after irradiation.

Effect of light-emitting diode (ʎ 627 nm and 945 nm ʎ) treatment on first intention healing: immunohistochemical analysis.

Collagen I is not only responsible for maintaining the integrity of most tissues due to its mechanical properties, but also for its active participation in the functionality of tissues because of its interaction with cells present in the extracellular matrix. The synthesis of collagen begins with tissue injury and remains until the end of the healing process. The use of non-coherent light for healing processes is still understudied.

The effects of transcranial LED therapy (TCLT) on cerebral blood flow in the elderly women.

During aging processes, there is a range of functional changes, where we can highlight the disease related to the central nervous system, such as Alzheimer disease and others forms of dementia. This study investigated the effects of transcranial light emitting diode (LED) on cerebral blood flow in healthy elderly women analyzed by transcranial Doppler ultrasound (TCD) of the right and left middle cerebral artery and basilar artery. Twenty-five noninstitutionalized elderly women (mean age 72 years old), with a cognitive status >24, were assessed using transcranial Doppler ultrasound on two separate occasions: pre-irradiation and post-transcranial LED therapy (TCLT).

Sulfonylurea induction of caffeine-enhanced insulin secretion and reduction of glycemic levels in diabetic rats.

Context: Caffeine can stimulate insulin secretion by attenuating hyperglycemia in diabetes models with significant reduction of pancreatic functional β cells. Knowledge of these mechanisms could contribute to new strategies for treating diabetes.

Objective: This study evaluated the effects of caffeine and physical exercise on glycemic and insulin responses in diabetic rats.

Macro and microscopic analysis of island skin grafts after low-level laser therapy.

Objective: To observe the effects of low intensity laser therapy in inflammation, wound healing and epithelialization of island skin grafts.

Methods: Twenty rats were subjected to this grafting technique and divided subsequently into two equal groups, one treated with laser and the other control.

Results: there was less inflammation, faster healing, epithelialization and keratinization in the laser-treated animals when compared to the untreated.

Analysis of electromyographic activity in spastic biceps brachii muscle following neural mobilization.

Introduction: Hypertonia is prevalent in anti-gravity muscles, such as the biceps brachii. Neural mobilization is one of the techniques currently used to reduce spasticity.

Objective: The aim of the present study was to assess electromyographic (EMG) activity in spastic biceps brachii muscles before and after neural mobilization of the upper limb contralateral to the hemiplegia.

The effect of manual therapy on masseter muscle pain and spasm.

Introduction: Orofacial pain and pain in the muscles of mastication are frequent symptoms of temporomandibular disorder. The masseter is the closet masticatory muscle to the surface and has the function of raising and retracting the mandible. This muscle has considerable strength and is one of the main muscles involved in the shredding of food It is therefore of utmost importance in the masticatory cycle and generally the most affected by pain and spasms.

Electromyographic analysis of biceps brachii muscle following neural mobilization in patients with stroke.

Objectives: The proposal of the present study is based on mobilizing the nervous system of the upper hemiplegic limb of stroke victims using the Upper Limb Neurodynamic Test (ULNT 1) and electromyographic analysis of the biceps brachii muscle.

Methods: A pre-experimental study was carried out with pretest and posttest repeated measurements on five stroke victims (4 men and 1 woman; mean age: 52.8 +/- 11 years), with Grade 1 and + 1 spasticity, according to the modified Ashworth scale.