Publications by authors named "Keren Doenyas"
Introduction: Aging is associated with a progressive decline in the capacity for physical activity. The objective of the current study was to evaluate the effect of an intermittent hyperbaric oxygen therapy (HBOT) protocol on maximal physical performance and cardiac perfusion in sedentary older adults.
Methods: A randomized controlled clinical trial randomized 63 adults (> 64yrs) either to HBOT (n = 30) or control arms (n = 33) for three months.
Article Synopsis
- Skin biopsies were used in a clinical trial to assess the effects of hyperbaric oxygen therapy (HBOT) on aging skin, targeting key aging hallmarks like telomere shortening and senescent cells.
- The study involved 70 participants, with 13 males undergoing skin biopsies before, during, and after a three-month HBOT treatment, showing significant improvements in collagen density, elastic fiber length, and blood vessel count.
- Results suggest that HBOT can effectively improve skin aging by promoting blood vessel growth and reducing senescent cells, marking a significant breakthrough in understanding treatments for aging in humans.
Background: Essential hypertension is an important risk factor for cerebrovascular diseases and a major cause of premature death in industrialized societies. A predisposing factor for essential hypertension is prehypertension: blood pressure (BP) values at rest that are at the higher end of the normal range. Abnormally enhanced cardiovascular responses to motor and emotional tasks have been found as predictors of essential hypertension.
View Article and Find Full Text PDFArticle Synopsis
- Aging leads to the loss of physiological capacity, primarily due to telomere shortening and cellular senescence.
- This study examined the impact of hyperbaric oxygen therapy (HBOT) on telomere length and senescent cell levels in healthy adults aged 64 and older, with 35 participants undergoing 60 daily HBOT sessions.
- Results showed a significant increase in telomere length (up to 37.63% in B cells) and a notable decrease in senescent T helper and T cytotoxic cells, suggesting that HBOT may have positive regenerative effects in aging populations.
Article Synopsis
- * The study involved 63 participants aged 64 and older, randomly assigned to either HBOT or a control group for three months, with results indicating significant cognitive improvements in the HBOT group, particularly in attention and information processing speed.
- * The HBOT group showed notable increases in cerebral blood flow in various brain regions, suggesting that HBOT may enhance cognitive functions in aging adults by promoting regional brain activity linked to key cognitive processes.
Individuals with a tendency toward abnormally enhanced cardiovascular responses to stress are at greater risk of developing essential hypertension later in life. Accurate profiling of continuous blood pressure (BP) reactions in healthy populations is crucial for understanding normal and abnormal emotional reaction patterns. To this end, we examined the continuous time course of BP reactions to aversive pictures among healthy participants.
View Article and Find Full Text PDF