[In vitro examination of the influence of lipase and amylase on dog's pancreas tissue incubated with endotoxins, phospholipase A2 or cytokines].

Proinflammatory cytokines are elevated during acute pancreatitis. The endotoxins and Phospholipase A2 (PLA2) also have important role in acute pancreatitis. The aim of this study was to determine, what factors are responsible for the tissue damage in acute pancreatitis.

[Changes in surgical therapy of pulmonary hydatid cysts].

The lung is the second most common site of hydatid cysts after the liver. The authors analyse retrospectively the results of patients treated with pulmonary hydatid cysts in the past 18 years, considering video-thoracoscopy. Twenty eight patients were treated during this period in 31 cases.

[Non septic, surgical complications and their treatment of acute necrotizing pancreatitis in 131 cases].

The authors analyse non septic, surgical complications and their treatment in 131 patients with acute necrotizing pancreatitis. Bleeding occurred in 13 patients 16 times. There were 3 cases with large intestine perforation, small intestine perforation twice in one patient and hydrothorax in 12 patients.

Quality of life following acute necrotizing pancreatitis.

Background/aims: The authors examine the quality of life of patients treated for acute necrotizing pancreatitis an average of 37.8 months following their illness.

Methodology: The questionnaire used in the examinations was a version of the Short Form-36 (SF-36) which was adapted to a Hungarian environment and included additional questions regarding the patient's illness.

CT-guided percutaneous peripancreatic drainage: a possible therapy in acute necrotizing pancreatitis.

Background/aims: To examine the effectiveness of therapeutic percutaneous drainage of peripancreatic fluid in the treatment of acute necrotizing pancreatitis.

Methodology: Twenty-eight patients treated for serious acute necrotizing pancreatitis (19 male, 9 female; average age 47.3 years) took part in the study.

[Therapeutic strategy in acute necrotizing pancreatitis].

We describe our therapeutic principles in connection with the treatment of 43 patients (30 male and 13 female) with acute necrotizing pancreatitis. The etiology of the disease was alcohol in 72.1%, gallstones in 23.

[Effect of intravenous and intraductal glucocorticosteroids in experimental acute pancreatitis in dogs].

We evaluated the effect of systematically and intraductally administered glucocorticosteroid on experimentally induced acute pancreatitis in dogs. We examined histological and macroscopic changes as well as conventional laboratory parameters. We suggest, that low dose intraductal injection of glucocorticosteroid could have protective effect in acute phase of pancreatitis.

[Evaluation of pancreatic anastomoses in the course of radical resection].

We examine the results of radical resections performed over a 10 year period at the 2nd Department of Surgery of the University of Debrecen Medical and Health Science Center Medical School of Medicine because of chronic inflammation, tumors of the papilla of Vater or tumors of the head of the pancreas. Pancreatoduodenectomy was performed in 134 patients, Whipple-type surgery in 11, and pylorus-preserving pancreatoduodenectomy in 123 patients. Three different types of reconstructive methods were used.

[Surgical treatment of intraabdominal hemorrhage in peliosis hepatis].

Introduction: Peliosis is an infrequent entity characterized by multiple blood-filled cavities mostly involving the liver. Peliosis hepatis usually appears as a rare autopsy finding in asymptomatic patients or in patients with chronic wasting diseases. However, peliosis hepatis may present as hepatic dysfunction or shock from hepatic rupture.

Evaluation of hemostatic changes and blood antioxidant capacity in acute and chronic pancreatitis.

Background/aims: We examined changes in hemostasis, in levels of total antioxidant capacity, and pancreatic enzymes (amylase, lipase) in patients with pancreatitis 1, 3 and 7 days after admission to the clinic, in order to evaluate the inflammatory processes in acute and chronic pancreatitis and to identify new prognostic markers.

Methodology: The rate of CD62 expression--a marker of platelet hyperactivity--and the rate of platelet-leukocyte aggregates were measured by flow cytometry. The connection between the parameters measured and the severity of pancreatitis and also the differences of the parameters in acute and chronic pancreatitis were investigated.

[Treatment of acute necrotizing pancreatitis: a comparative study].

The authors compared the therapeutic results of acute necrotizing pancreatitis during two separate time periods involving 97 and 24 patients, respectively. In the group "A", the time period lasted between May 31, 1991 and December 31, 1997. This group consisted of 97 patients, who, in addition to undergoing intensive treatment and antibiotic prophylaxis, later underwent late necrectomy and closed peripancreatic drainage.

[CT-guided percutaneous drainage in the treatment of acute necrotizing pancreatitis].

The authors analysed the results of the treatment of 24 patients with acute necrotizing pancreatitis. Besides intensive and operative treatment prophylactic antibiotics, early naso-jejunal feeding, CT guided percutaneous peripancreatic drainage are favourable to avoid septic complications and to postpone the first operation. In 11 patients percutaneous drainage was performed.

[Necrosis of the galea as rare complication of infection of a traumatic temporal hematoma].

Authors report a case of infective traumatic temporal haematoma causing septic focus. The suppurative inflammation developed two weeks after the trauma causing necrosis of an extensive part of the galea on a big area of the crown of head. A septic process increased producing necrotic alteration of the affected periosteum of the cranial bone and plegmon in the tissue of the neck.

[Association of carcinoid tumor of the appendix and Crohn disease (case report and review of the literature)].

The authors describe the coexistence of the carcinoid of the appendix and Crohn's disease. In the case of their woman patient the carcinoid was identified with the examination of the resected ileoascendent part of the bowel resulting of the complication of the Crohn's disease. 10 similar association is known in the literature but none of the patients had the signs of the carcinoid syndrome.

Influence of NaCl supplementation on vasopressin secretion and water excretion in premature infants.

The study was carried out to assess the possible involvement of excess AVP and free water retention in the development of late hyponatremia by comparing the postnatal course of plasma AVP and urinary excretion of AVP and sodium as well as creatinine, osmolar and free water clearances in premature infants with (group S) and without (group NS) NaCl supplementation. Plasma total protein and albumin concentrations were also determined. Group NS consisted of 8 infants with a birth weight of 1,150-1,730 g (mean: 1,440 g) and gestational age of 28-32 weeks (mean: 30.

[Intra-partum ethamsylate (dicynone) administration in the prevention of cerebral hemorrhage in premature infants].

Dicynone has been in use in all premature births prophylactically since 1987 by the authors. The administration of the drug begins before or during delivery. The diagnoses of cerebral haemorrhage was established on autopsy and the cases were compared with the previous years when Dicynone was not administered.

Postnatal changes in blood spot 17-hydroxyprogesterone level in healthy preterm and full-term neonates.

Blood spot 17OH-P concentrations were determined in 14 healthy premature (mean birthweight 1439 g, mean gestational age 30 weeks) and full-term newborn infants (mean birthweight 3532 g, mean gestational age 39.2 weeks) during the first five weeks of life to provide reference data for infants with various gestational and postnatal ages. It was demonstrated that with advancing age there was an abrupt fall in 17OH-P from 296.

Change in phage-sensitivity of Shigella flexneri strains. I. Changes in virulence and phage-sensitivity.

In the course of repeated passaging of virulent Shigella flexneri cultures in liquid media, avirulent variants and variants of reduced virulence appeared. They were easily recognizable by their colonial morphology. The avirulent variants became sensitive to certain phages not lysing the original virulent strains.

Changes in phage-sensitivity of Shigella flexneri strains. II. The F-like character of Ms2-sensitive variants.

Variants sensitive to male specific phage Ms2 appeared among Ms2 non-sensitive Shigella flexneri cultures in the course of liquid medium passages. Sensitivity to Ms2 was lost on acridine orange treatment and was transferable into Ms2 non-sensitive variants. The Ms2 sensitive variants had fimbrial antigen.