Determination of Key Technical Parameters in the Study of New Pressure Sealing Technology for Coal Seam Gas Extraction.

Coal is affected by the concentrated stress disturbance of mining, the disturbance of drilling hole formation, and the concentrated stress of coal shrinkage and splitting of gas desorption from the hole wall; these result in a large number of secondary cracks that collect and leak gas. As a result, it is difficult for the coal seam sealing process to meet engineering quality sealing requirements, which results in problems such as low gas concentration during the extraction process. In this paper, based on the analysis of coal pore and fissure characteristics, and in view of the current situation of gas drainage and sealing in this coal seam, combined with the existing grouting and sealing technology, it is proposed to use pressure grouting and sealing to realize the sealing of deep coal bodies in the hole wall.

Simple and sensitive colorimetric sensors for the selective detection of Cu(ii).

A simple, sensitive colorimetric probe for detecting Cu(ii) ions with fast response has been established with a detection limit of 2.82 μM. UV-Vis spectroscopy along with metal ion response, selectivity, stoichiometry, competition was investigated.

Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling.

The complex microenvironment of malignant gliomas plays a dynamic and usually cancer-promoting role in glioma progression. Astrocytes, the major stromal cells in the brain, can be activated by glioma microenvironment, resulting in a layer of reactive astrocytes surrounding the gliomas. Reactive astrocytes are universally characterized with the upregulation of glial fibrillary protein and glycoprotein podoplanin.