Publications by authors named "Keping Peng"
Article Synopsis
- * Researchers created an FA mouse model using ovalbumin and found that intestinal B cells from FA mice produced significantly lower levels of IL-10 compared to control mice, indicating impaired immune function.
- * The study demonstrated that treatment with CpG could restore IL-10 production in FA B cells by altering the methylation status of a specific promoter, suggesting that CpG may enhance the effectiveness of allergen-specific immunotherapy for food allergies.
Objectives: The present study aimed to investigate the relationship between male hormones and metabolic dysfunction-associated fatty liver disease (MAFLD) in males.
Methods: Data from the Fangchenggang Area Male Health and Examination Survey (FAMHES) were used to analyze the male hormone levels between MAFLD patients and controls. Univariate and multivariate logistic regression analyses were performed to identify risk factors for MAFLD.
The pathogenesis of ulcerative colitis (UC) is unclear. House dust mite (HDM) is associated with immune inflammation in the body. This study is designed to identify the association between HDM and UC clinical symptoms.
View Article and Find Full Text PDFInterleukin 10 (IL-10)-producing B cells (B10 cells) are a canonical cell fraction for regulating other activities of immune cells. Posttranscriptional modification of IL-10 in B10 cells is not yet fully understood. Short-chain fatty acids play an important role to regulate the functions of immune cells.
View Article and Find Full Text PDFBackground: Allergen-specific immunotherapy (AIT) is the mainstay in the treatment of allergic diseases, but the therapeutic effects of AIT need to be improved. CD38 B cells are an immune cell fraction involved in the pathogenesis of allergic diseases as well as in immune regulation.
Objective: We sought to elucidate the role of antigen-specific CD38 B cells in AIT.
Characteristics of electrophysiological changes in the process of astrocytes pyroptosis after hyperoxia exposure.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
July 2020
Objectives: To observe the electrophysiological changes of astrocytes in the process of hyperoxia induced apoptosis and analyze the relationship between electrophysiological characteristics and morphological changes.
Methods: Astrocytes were exposed to 90% hyperoxia for 12-72 h. The electrophysiological characteristics of astrocytes in each group were detected by patch clamp technique, and the morphological characteristics of astrocytes were observed at the same time.
Objectives: The aim of this study was to investigate whether the measurement of brain tissue stiffness using acoustic radiation force impulse (ARFI) elastography with virtual touch tissue quantification can improve the early detection of neonatal hypoxic-ischemic brain damage in rats.
Methods: Seven-day-old Sprague-Dawley rats were randomly assigned to 3 groups: the mild asphyxia (n = 30), moderate asphyxia (n = 30), and sham control (n = 10) groups. Rats in the mild and moderate asphyxia groups were exposed to 8% oxygen (hypoxia) for 30 and 60 minutes, respectively, at 1 hour after ligation of the right common carotid artery.
Background: Dyslipidemia is a risk factor for nonalcoholic fatty liver disease (NAFLD). The aim of our study was to determine the associations of serum lipid indexes with NAFLD in adult males.
Materials And Methods: In this cross-sectional study, 830 patients with NAFLD and 2,357 healthy individuals were assessed.
[Effect of yigu capsule contained serum on mRNA and protein expression of estrogen receptor in osteoblast rats].
Zhongguo Zhong Xi Yi Jie He Za Zhi
April 2005
Objective: To explore the effect of Yigu capsule contained serum on mRNA and protein expression of osteoblast estrogen receptor (ER), for investigating the mechanism of its preventing and treating osteoporosis by means of regulating estrogen.
Methods: Osteoblasts separated from newborn SD rats were cultured, and divided into 3 groups after being passaged, i.e.
Objective: The effects of Yigu Capsule on NO and NOS of osteoblasts were studied.
Methods: (1) Forty 12-month old Sprague-daweley female rats were divided into randomly four groups (Yigu Capsule high dose group, medium dose group and low dose group; saline group), the drug-containing serum and control serum were prepared. (2) The new-born Sprague-daweley rat Osteoblasts were cultured with different Yigu Capsule drug-containing serum concentration and at different exposure time.
Objective: To investigate the effect of rats sera containing Benefiting-bone Capsule (BBC) on the cell proliferation of skull osteoblast in neonatal SD rats.
Methods: Forty female SD rats, aged 12 months, were randomly divided into 4 groups including N.S.
Objective: To study the efficacy of "Bushen Huoxue Liquid" (BSHXL) in male rats with osteoporosis induced by dexamethasone (DM) and its mechanism.
Methods: Forty-six male Sprague-Dawley rats at 18 months of age were chosen. They were divided into four groups, BSHXL and DM were administered appropriately for 12 weeks.