Deep palm burn treated with enzymatic debridement followed by autologous skin cell suspension: a case study.

Despite improvements in treatment methods and outcomes, burns remain one of the principal causes of mortality and morbidity worldwide. Burns involving the hands are estimated to occur in >80% of people with burns. Hand burns have also been associated with long-term social, psychological and physical consequences that can impede a patient's full reintegration to the community and decrease their overall quality of life.

Force-Temporal Characteristics of EEG-EMG Coherence during Isometric Contraction of Lateral Head of Gastrocnemius Muscle.

Coherence between an electroencephalogram (EEG) and an electromyogram (EMG) of the soleus (SOL) muscle during an isometric contraction is observed in the beta-band (15 to 35 Hz) regardless of the contraction force. However, the dynamics on how a variation in coherence occurs over time in the head of the gastrocnemius (GLH) muscle, which is also known to have the same role as the soleus muscle, have yet to be considered. In this study, we focused on GLH and measured an EEG and EMG taken of the GLH muscle when executing an isometric contraction through the dorsiflexion of the right ankle joint for a 1-min period.

Synthesis of Non-Natural Heteroaminopolysaccharides by α-Glucan Phosphorylase-Catalyzed Enzymatic Copolymerization: α(1→4)-Linked Glucosaminoglucans.

Thermostable α-glucan phosphorylase-catalyzed enzymatic copolymerization of α-d-glucose 1-phosphate (Glc-1-P) with its analogue monomer, α-d-glucosamine 1-phosphate (GlcN-1-P), from a maltotriose primer was performed to produce non-natural heteroaminopolysaccharides composed of Glc/GlcN units, that is, α(1→4)-linked glucosaminoglucans. The GlcN units in the products were further converted to N-acetyl-d-glucosamine (GlcNAc) units by N-acetylation. The structures of the products were evaluated by the MALDI-TOF MS, (1)H NMR, and (1)H-(1)H COSY NMR measurements, which were completely different from those of the natural glycosaminoglycans.

Synthesis of chitin and chitosan stereoisomers by thermostable α-glucan phosphorylase-catalyzed enzymatic polymerization of α-D-glucosamine 1-phosphate.

The relationship between two aminopolysaccharide stereoisomers, namely α-(1→4)- and β-(1→4)-linked (N-acetyl)-D-glucosamine polymers, is of significant interest within the field of polysaccharide science, as they correspond to amino analogs of the representative abundant natural polysaccharides, viz. amylose and cellulose. While the latter glucosamine polymer is the basis of well-known natural polysaccharides, chitin and chitosan (linear polysaccharides composed of β-(1→4)-linked N-acetyl-D-glucosamine and D-glucosamine), to the best of our knowledge, the former (α-(1→4)-linked) has not been observed in nature.