Multidisciplinary therapeutic strategy with appropriate timing and modalities for treating cervicofacial lymphatic malformations in children.

Purpose: The study reviewed a multidisciplinary approach to treating cervicofacial lymphatic malformations (CFLMs) in children.

Methods: Between 2007 and 2023, 53 children with CFLMs were treated with the median on-set age of 5 months (0-165) at our institute. For infants, airway management, including possible tracheotomy was prioritized, and a "wait-and-see" policy was adopted to expect spontaneous regression.

Maternal interpretation of infant emotions related to mothers' mindfulness and mother-infant stress.

We aimed to identify maternal characteristics predicting interpretation of infant emotions, as well as relations between such interpretations and mother-infant stress. Specifically, we investigated (1) prospective associations between maternal dispositional mindfulness and interpretation of infant emotions, and (2) concurrent associations between maternal interpretation of infant emotions and mothers' and infants' cortisol during a dyadic stressor in a non-clinical community sample ( = 78) of mother-infant dyads. Mothers completed the Five Facet Mindfulness Questionnaire at 3 months postnatal, and the IFEEL Picture infant emotion interpretation task at 6 months postnatal.

Long-term outcomes of PDT for centrally-located early lung cancers with tumor diameters > 2.0 cm.

Background: Photodynamic therapy (PDT) is used for the treatment of centrally-located early lung cancers (CLELCs) and is recommended for tumors ≤ 1.0 cm in diameter. We previously reported that PDT using talaporfin sodium, second-generation photosensitizer, for tumors > 1.

Organic Molecular Conductors Based on Tetramethyl-TTP: Structural and Electrical Properties Modulated by the Anion Size and Shape.

The tetramethyl derivative of bis-fused tetrathiafulvalene, 2,5-bis(4,5-dimethyl-1,3-dithiol-2-ylidene)-1,3,4,6-tetrathiapentalene (TMTTP), has been successfully synthesized. Most of the radical cation salts consisting of TMTTP feature a high electrical conductivity of σ = 10 to 10 S cm on a single crystal. The anion shape and size of TMTTP conductors modulate the electrical properties.

Functionally modified chitotriosidase catalytic domain for chitin detection based on split-luciferase complementation.

In this study, we applied a luciferase-fragment complementation assay for chitin detection. When luciferase-fragment fused chitin-binding proteins were mixed with chitin, the reconstituted luciferase became active. The recombinant chitin-binding domain (CBD) and a functionally modified catalytic domain (CatD) of human chitotriosidase were employed for this method.

New Technique for Introducing a Surgical Stapler during Robot-Assisted Lobectomy for Lung Cancer.

Background: The da Vinci Si version robot lacks a vascular stapler that can be controlled by the operating surgeon at the surgical console when dividing pulmonary vessels. Therefore, to initiate and safely perform robotic anatomical lobectomy for lung cancer, it is important to develop a safe method for introducing a surgical stapler.

Methods: We performed a retrospective study of the first 42 consecutive patients who underwent robotic lobectomy for lung cancer at Nippon Medical School Hospital between January 2019 and December 2020.

Development of small high-voltage AC power supply for a dielectric barrier discharge plasma actuator.

A dielectric-barrier discharge plasma actuator (DBDPA) is a promising flow control device that can prevent flow separation around an airfoil using electrical discharges. Miniaturizing the DBDPA power supply remains a crucial technological challenge because its size and weight determine the performance of fluid devices equipped with this type of actuator. In this study, we propose a compact high-voltage AC power supply for a DBDPA intended for installation on small airplanes, including unmanned aerial vehicles.

[Therapeutic Strategies for Metachronous Multiple Primary Lung Cancer].

Backgrounds: It is not uncommon to encounter metachronous primary lung cancer after surgical treatment along with the increase in the elderly patients. In consideration of increasing number of such patients, it is necessary to take various treatment strategies.

Methods: In order to establish a treatment strategy for multiple lung cancer, we retrospectively examined multiple lung cancer cases operated for primary lung cancer in our department from January 2013 to December 2019, and the future treatment strategy was examined.

Hydration Effect on Positron Binding Ability of Proline: Positron Attachment Induces Proton-Transfer To Form Zwitterionic Structure.

The positron binding abilities of proline and its hydrated clusters were theoretically studied using multicomponent molecular orbital (MC_MO) calculations. Low-lying equilibrium structures of the neutral proline·(HO) ( n = 0-2) clusters were systematically explored with the aid of global reaction route mapping code. The positron binding energies were then calculated for the equilibrium structures.

Nuclear quantum effects in the direct ionization process of pure helium clusters: path-integral and ring-polymer molecular dynamics simulations on the diatomics-in-molecule potential energy surfaces.

The direct photoionization of pure helium clusters, He (n = 100, 200 and 300), and its subsequent short-time process have been studied by path integral molecular dynamics (PIMD) and ring-polymer molecular dynamics (RPMD) simulations that can effectively describe the nuclear quantum effects in large systems. The modified diatomics-in-molecule (DIM) model [Calvo et al., J.

Reduction of OH vibrational frequencies in amino acids by positron attachment.

Positron affinities have been calculated for five amino acid molecules (asparagine, cysteine, glycine, proline, and serine) with the intramolecular COOH···NH  hydrogen-bonded motif as a function of the OH distance using two computational methods, namely multicomponent molecular orbital theory and pseudopotential model. Since the elongation of the carboxylic OH bond leads to the formation of highly polarized zwitterionic amino acid with COO ···NH  structure, the calculated positron affinity significantly increases with the elongation of the OH distance. This indicates that the OH bond strength is significantly weakened by positron attachment.

Bayesian Estimation of Phase Dynamics Based on Partially Sampled Spikes Generated by Realistic Model Neurons.

A dynamic system showing stable rhythmic activity can be represented by the dynamics of phase oscillators. This would provide a useful mathematical framework through which one can understand the system's dynamic properties. A recent study proposed a Bayesian approach capable of extracting the underlying phase dynamics directly from time-series data of a system showing rhythmic activity.

Molecular characterization and validation of commercially available methods for haptoglobin measurement in bottlenose dolphin.

Haptoglobin (Hp) is a positive acute-phase protein and a valuable marker of inflammation in both human and veterinary medicine. The aim of this study was to validate the molecular characterization of Hp in dolphins and to validate commercially available Hp measurement methods such as Hp-ELISA (originally designed for pigs) and Hp-hemoglobin (Hb) binding assay. The dolphin Hp (dHp) amino acid sequence appeared most similar to pig Hp by sequence homology and phylogenetic clustering.