Publications by authors named "Kento Matsuda"
Modeling a Microtubule Filaments Mesh Structure from Confocal Microscopy Imaging.
Micromachines (Basel)
September 2020
Article Synopsis
- This study presents a new modeling technique for creating supermolecular structures of microtubules to develop materials that generate force using motor proteins.
- Researchers utilized confocal laser scanning microscopy (CLSM) to gather 3D density data, which was then analyzed using Blender to build a 3D model of microtubule networks.
- Although motor proteins were not directly observed, they were incorporated into the model to simulate the contraction of this artificial muscle, demonstrating potential applications for enhancing contractile molecular systems.
DNA has been well-known for its applications in programmable self-assembly of materials. Nonetheless, utility of DNA origami, which offers more opportunity to realize complicated operations, has been very limited. Here we report self-assembly of a biomolecular motor system, microtubule-kinesin mediated by DNA origami nanostructures.
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