Publications by authors named "Kento Kono"
A 61-year-old man presented to our hospital with a chief complaint of chronic cough. He was diagnosed with lung squamous cell carcinoma at clinical stage cT2aN3M1a. He received chemotherapy up to the fourth line, but both the primary tumor and lymph node metastases increased in size.
View Article and Find Full Text PDFA 45-year-old man visited our hospital with a chronic cough and breathing difficulties. Chest computed tomography revealed diffuse granular shadows. Mycobacterium avium (M.
View Article and Find Full Text PDFIntroduction: Combination therapy of atezolizumab and chemotherapy has become the standard treatment for small-cell lung cancer. Immune-related adverse events (irAEs) can occur during immune checkpoint inhibitor administration. A few reports exist on pure red cell aplasia (PRCA) as an irAE after atezolizumab treatment.
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- A 71-year-old man with advanced lung adenocarcinoma was treated with chemotherapy and immunotherapy, specifically carboplatin, pemetrexed, and pembrolizumab, starting in June 2020.
- He continued maintenance therapy with pemetrexed and pembrolizumab until November 2022, but developed fever and severe fatigue in December 2022, with inconclusive tests for the cause of infection.
- The patient was suspected to have immune-related cytokine release syndrome (CRS) and improved after being treated with prednisolone, highlighting that CRS can occur long after starting immune checkpoint inhibitor therapy.
Article Synopsis
- Older patients (over 75) with severe respiratory failure have a high mortality rate and struggle with daily activities, notably those who are frail.
- A study at Shimane University Hospital analyzed the outcomes of 32 patients who were intubated and ventilated, comparing frail individuals to self-sufficient ones, finding that 50% of frail patients died compared to 33% of self-sufficient patients.
- The results highlight the poor prognosis for frail patients, underscoring the need for careful evaluation before initiating intensive care treatments like intubation and ventilation.
A 59-year-old man presented with esophageal achalasia complicated by lipoid pneumonia. Dysphagia and diffuse ground-glass shadows on computed tomography led to the diagnosis of esophageal achalasia. An analysis of bronchoalveolar lavage (BAL) revealed yellow BAL fluid, with two distinct layers.
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