Publications by authors named "Kentaro Sekizawa"
Article Synopsis
- The study examines the relationship between the immune microenvironment and the effectiveness of preoperative chemotherapy in rectal cancer patients.
- Researchers analyzed tumor samples from 65 patients who underwent chemotherapy and surgery and looked at specific T lymphocyte markers.
- Results indicated that lower levels of regulatory T cell (Treg) infiltration were associated with better tumor response and reduction rates after chemotherapy, suggesting Tregs could be a useful marker for predicting treatment success.
Aim: To investigate the long-term oncologic outcomes and prognostic factors in patients with obstructive colorectal cancer (CRC) at multiple Japanese institutions.
Methods: We identified 362 patients diagnosed with obstructive colorectal cancer from January 1, 2002 to December 31, 2012 in Yokohama Clinical Oncology Group's department of gastroenterological surgery. Among them, 234 patients with stage II/III disease who had undergone surgical resection of their primary lesions were analyzed, retrospectively.