Maximizing the total population with logistic growth in a patchy environment.

This paper is concerned with a nonlinear optimization problem that naturally arises in population biology. We consider the population of a single species with logistic growth residing in a patchy environment and study the effects of dispersal and spatial heterogeneity of patches on the total population at equilibrium. Our objective is to maximize the total population by redistributing the resources among the patches under the constraint that the total amount of resources is limited.

Rho-associated protein kinase inhibitor induced morphological changes in type VI collagen in the human trabecular meshwork.

Aims: To investigate morphological changes in type VI collagen in the human trabecular meshwork associated with the rho kinase inhibitor ripasudil.

Methods: This cross-sectional study evaluated the effects of ripasudil eye drop administration (RA) or no ripasudil eye drop administration (NRA) in patients with primary open-angle glaucoma (POAG; age range 60-80 years) who underwent conventional outflow reconstruction between December 2015 and September 2016 at Tokai University Hachioji Hospital. The juxtacanalicular tissue was removed and imaged using transmission electron microscopy.