Synthesis of -(acyloxy)--alkynylamides generation of "C" from hypervalent alkynyliodane and a weak base.

The first synthesis of -(acyloxy)ynamides was realized through the coupling of -(acyloxy)amides and hypervalent alkynyliodane under mild conditions. This reaction probably involves biradical species ("C") generation and radical processes. Furthermore, we also demonstrated that -(acyloxy)ynamide could be transformed into a -sulfonylimidate derivative by a copper catalyst.