Publications by authors named "Kent Cheung"
Objective: Focused Abdominal Sono-graphy for Trauma (FAST) is widely used for the detection of intraperitoneal free fluids in patients suffering from blunt abdominal trauma (BAT). This study aimed at assessing the diagnostic accuracy of this investigation in a designated trauma centre.
Methods: This was a retrospective study of BAT patients over a 6 year period seen in a trauma centre in Hong Kong.
Article Synopsis
- Chronic hepatitis C genotype 6 is prevalent in Hong Kong, particularly among intravenous drug users, and past treatment responses have varied greatly among small study groups.
- A study involving 70 patients compared the effectiveness of pegylated interferon and ribavirin in treating genotype 6 versus genotype 1.
- Results showed genotype 6 patients had significantly better early and sustained virological responses, indicating they respond more favorably to treatment than those with genotype 1.
Polyethylenimines (PEI) are often inefficient in gene knockdown experiments with small interfering RNA (siRNA), presumably due to the strong complexing properties. A more efficient and potentially degradable oligoethylenimine-based carrier was synthesized by the condensation of 800 molecular weight PEI oligomers with hexanedioldiacrylate. Reaction conditions were chosen such that Michael reaction occurs followed by complete N-acylation of all residual ester bonds resulting in beta-aminopropionamide linkage sites and an average molecular weight of 30,000.
View Article and Find Full Text PDF