Publications by authors named "Kensuke Asakura"

Article Synopsis
  • This study investigates the effectiveness of bowel preparation using polyethylene glycol lavage (PEL) in patients with suspected colonic diverticular bleeding (CDB) who underwent early colonoscopy within 24 hours.
  • The analysis, which included data from 10 institutions, revealed that patients prepared with PEL had shorter hospital stays and higher rates of successful cecal intubation compared to those without PEL preparation.
  • The findings suggest that PEL is beneficial for early colonoscopy in CDB cases, with no significant difference in adverse events or treatment outcomes between the two groups.
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Background And Aim: Few studies have evaluated risk factors for short-term re-bleeding in patients with colonic diverticular bleeding (CDB). We aimed to reveal risk factors for re-bleeding within a month in patients with CDB.

Methods: We retrospectively analyzed clinical course of patients with CDB diagnosed at 10 institutions between 2015 and 2019.

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We present the case of a 17-year-old male patient with ulcerative colitis (UC) under infliximab therapy and a family history of IgA vasculitis (IgAV). During a maintenance infliximab session, he developed palpable purpura, abdominal pain, and hematochezia. Computed tomography and endoscopy revealed findings compatible with gastrointestinal manifestations of IgAV.

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Article Synopsis
  • Magnifying endoscopic classification systems, like the JNET, help predict the nature and depth of colorectal tumors, but differences in observer opinions can lead to subjective diagnoses.
  • A study analyzed endoscopic images of 169 colorectal tumors to evaluate endoscopic microvascular density (eMVD) as a more objective diagnostic tool.
  • Results showed that eMVD is significantly higher in carcinomas compared to adenomas, with a cutoff value of 0.133 providing moderate sensitivity (56.9%) and specificity (67.0%) for distinguishing between the two.
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Objective Indigo naturalis (IN) is a traditional Chinese medicine that has recently been reported to be effective for ulcerative colitis (UC). The aim of this study was to evaluate the efficacy and safety of IN. Methods We performed a retrospective observational study for 14 patients with UC treated with IN from October 2015 to December 2016.

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Aim: To determine appropriate fecal calprotectin cut-off values for the prediction of endoscopic and histologic remission in Japanese patients with ulcerative colitis (UC).

Methods: We performed a cross-sectional observational study of 131 Japanese patients with UC and measured fecal calprotectin levels by fluorescence enzyme immunoassay. The clinical activity of UC was assessed with the partial Mayo score (PMS).

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Rationale: Familial Mediterranean fever (FMF) is the most common form of autoinflammatory disease. We report a rare case of FMF with gastrointestinal lesions mimicking Crohn disease.

Patient Concerns: A 21-year-old Japanese man was referred to our institution, complaining of refractory diarrhea and weight loss of 14 kg during the past two years.

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Article Synopsis
  • - The study investigated the relationship between clinicopathological features, mucin phenotypes, and endoscopic findings in non-ampullary duodenal epithelial tumors (NADETs) using crystal violet staining (ME-CV).
  • - Researchers categorized 55 NADET patients based on mucin phenotypes and identified four distinct ME-CV patterns, finding significant differences among these groups.
  • - Results indicated that gastric-type tumors frequently exhibited a "pinecone" pattern, particularly those associated with pyloric gland adenomas, and had distinct endoscopic appearances compared to other mucin types.
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Familial amyloid polyneuropathy (FAP) is an autosomal dominant disease associated with the mutations in the transthyretin gene. To date, the endoscopic findings of the small-bowel lesions of FAP have never been described. We report a rare case of FAP with gastrointestinal involvement.

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