Synthesis of nanosized porous hydroxyapatite granules in hydrogel by electrophoresis.

Nanosized porous hydroxyapatite (HA) granules are expected to be useful as DNA and drug carriers for cells. We attempted to synthesize nanosized HA granules in an agarose gel by electrophoresis of calcium and phosphate ions. Wells were prepared on an agarose gel, and a CaCl(2) solution was placed in the wells on the positive side and a Na(2)HPO(4) solution was placed in the wells on the negative side.