Publications by authors named "Kenny Wang"
Article Synopsis
- A study investigated the incidence and characteristics of traumatic iritis in Olmsted County, Minnesota, over a decade, identifying 156 cases with an adjusted rate of 10.7 per 100,000 per year.
- The majority of affected individuals were young males, particularly from the Black community, with the average age at diagnosis being 33 years.
- Common causes of traumatic iritis included sports injuries, assaults, scratches, and work-related incidents, with most patients experiencing unilateral symptoms and varying follow-up durations.
Purpose: To describe the outcomes of hyperbaric oxygen therapy (HBOT) for patients with central retinal artery occlusion (CRAO) at a single tertiary care center.
Design: Retrospective clinical cohort study.
Methods: Medical records of all patients diagnosed with CRAO who received HBOT at Mayo Clinic in Rochester, Minnesota from January 1, 2009 to December 31, 2020 were reviewed to confirm diagnosis, time from onset to presentation, exam findings, treatments, and follow-up data.
Purpose: To identify demographic and clinical factors associated with delayed diagnosis in patients with primary vitreoretinal lymphoma (VRL).
Methods: Retrospective, tertiary referral center-based cohort study of all patients at Mayo Clinic in Rochester, Minnesota, with a biopsy-proven diagnosis of VRL from January 1, 2000, to October 31, 2022.
Results: There were 87 patients included during the 22-year study period with 73 patients (83.
Article Synopsis
- The study analyzed the occurrence and features of ocular adnexal tumors in Olmsted County, Minnesota, over a decade from 2006 to 2015.
- During this period, 717 patients were diagnosed with ocular adnexal tumors, predominantly benign eyelid lesions, with an incidence rate of 59.7 per 100,000 individuals per year.
- The findings highlighted that while most tumors were benign, a significant number of malignant cases were also identified, particularly basal and squamous cell carcinomas, underscoring the need for awareness in clinical practice for diagnosis and referrals.
A Case of Nasoseptal Flap Reconstruction for Refractory Medial Canthal Fistula.
Ophthalmic Plast Reconstr Surg
November 2024
Sino-orbital cutaneous fistulas (SOCFs) are a rare and challenging complication from conditions including granulomatosis with polyangiitis. SOCFs are difficult to manage due to poor vascular supply, compromised tissue, and systemic immunocompromise, which lead to a high rate of recurrence. Given the overall rarity of SOCFs, optimal surgical repair remains controversial, with options ranging from conservative management, onlay grafts, and vascularized flaps.
View Article and Find Full Text PDFIntroduction: The aim of this study was to determine the predictive value of International Classification of Diseases, 9th Revision (ICD-9) billing codes for identifying ocular oncology diagnoses.
Methods: Population-based retrospective cohort study of all Olmsted County, Minnesota residents with any ocular neoplasm-related ICD-9 code from January 1, 2006 to October 1, 2015. All medical records were reviewed for confirmation of ocular neoplasm.
Purpose: To investigate the incidence and clinical characteristics of pediatric ocular tumors in a US Midwestern county population.
Methods: Retrospective population-based cohort study of all Olmsted County, Minnesota, pediatric patients (<18 years old) diagnosed with any ocular neoplasm from January 1, 2006, to December 31, 2015. Subjects were identified via the Rochester Epidemiology Project, a record-linkage system that captures virtually all medical care provided in this county.
Neutrophil Extracellular Traps (NETs) are a key form of pro-inflammatory cell death of neutrophils characterized by the extrusion of extracellular webs of DNA containing bactericidal killing enzymes. NETosis is heavily implicated as a key driver of host damage in autoimmune diseases where injurious release of proinflammatory enzymes damage surrounding tissue and releases 70 known autoantigens. Recent evidence shows that both neutrophils and NETosis have a role to play in carcinogenesis, both indirectly through triggering DNA damage through inflammation, and directly contributing to a pro-tumorigenic tumor microenvironment.
View Article and Find Full Text PDFDescription Mucormycosis is a rare devastating fungal infection with a high mortality rate often associated with diabetic and immunosuppressed individuals. However, infections found in postoperative states and in immunocompetent patients are rare. Systemic liposomal amphotericin is viewed as a first line treatment for mucormycosis in addition to aggressive debridement to prevent the spread of infection.
View Article and Find Full Text PDFTUG tethering proteins bind and sequester GLUT4 glucose transporters intracellularly, and insulin stimulates TUG cleavage to translocate GLUT4 to the cell surface and increase glucose uptake. This effect of insulin is independent of phosphatidylinositol 3-kinase, and its physiological relevance remains uncertain. Here we show that this TUG cleavage pathway regulates both insulin-stimulated glucose uptake in muscle and organism-level energy expenditure.
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