Correction: Sundaraj et al. Cloning, Expression and Functional Characterization of a Novel α-Humulene Synthase, Responsible for the Formation of Sesquiterpene in Agarwood Originating from . 2023, , 8989-9002.

Afiq Adham Abd Rasib and Roohaida Othman were not included as authors in the original publication [...

Seroprevalence and molecular characterisation of infectious bronchitis virus (IBV) in broiler farms in Sabah, Malaysia.

Background: Infectious bronchitis virus (IBV) is classified as a highly contagious viral agent that causes acute respiratory, reproductive and renal system pathology in affected poultry farms. Molecular and serological investigations are crucial for the accurate diagnosis and management of IBV.

Objectives: The purpose of this study was to determine the seroprevalence of IBV and to characterise the circulating IBV in poultry farms in Sabah Province, Malaysia.

Complete genome sequence data of an Antarctic bacterium sp. EM1 from the freshwater lake of the King George Island.

sp. EM1 is a cold-adapted bacterium isolated from the Antarctic region, which was known to exhibit mannan-degrading activity. Accordingly, this strain not only promises a cell factory for mannan-degrading enzymes, widely used in industry but also serves as a model organism to decipher its cold adaptation mechanism.

Cloning, Expression and Functional Characterization of a Novel α-Humulene Synthase, Responsible for the Formation of Sesquiterpene in Agarwood Originating from .

This study describes the cloning, expression and functional characterization of α-humulene synthase, responsible for the formation of the key aromatic compound α-humulene in agarwood originating from . The partial sesquiterpene synthase gene from the transcriptome data of was utilized for full-length gene isolation via a 3' RACE PCR. The complete gene, denoted as , has an open reading frame (ORF) of 1671 bp and encodes for a polypeptide of 556 amino acids.

Timeline of SARS-CoV-2 Transmission in Sabah, Malaysia: Tracking the Molecular Evolution.

Background: The COVID-19 pandemic poses an unprecedented public health challenge in Malaysia. The impact of COVID-19 varies between countries, including geographically divided states within a country. The deadly transmission of COVID-19 has taken a heavy toll in Sabah, Malaysia's third most populous state, contributing nearly 10% to the recorded national death toll as of 31 December 2022.

Whole genome sequence data of a marine bacterium PBVC038, associated with toxic harmful algal bloom.

(PBVC038) was isolated from a harmful algal bloom event caused by the toxic dinoflagellate var. () in Sepanggar Bay, Sabah, Malaysia, in December 2012. Blooms of are frequently linked to paralytic shellfish poisoning, resulting in morbidity and mortality.

Small RNA datasets of drug-susceptible strains from Sabah, Malaysia.

These datasets present a list of small RNAs from three drug-susceptible strains isolated from Sabah, Malaysia. Sputum samples were obtained from three tuberculosis patients belonging to different districts. The bacteria were detected using GeneXpert MTB/RIF, isolated and cultured in BACTEC MGIT 320, and tested for their drug susceptibility.

Current Understanding on the Genetic Basis of Key Metabolic Disorders: A Review.

Advances in data acquisition via high resolution genomic, transcriptomic, proteomic and metabolomic platforms have driven the discovery of the underlying factors associated with metabolic disorders (MD) and led to interventions that target the underlying genetic causes as well as lifestyle changes and dietary regulation. The review focuses on fourteen of the most widely studied inherited MD, which are familial hypercholesterolemia, Gaucher disease, Hunter syndrome, Krabbe disease, Maple syrup urine disease, Metachromatic leukodystrophy, Mitochondrial encephalopathy lactic acidosis stroke-like episodes (MELAS), Niemann-Pick disease, Phenylketonuria (PKU), Porphyria, Tay-Sachs disease, Wilson's disease, Familial hypertriglyceridemia (F-HTG) and Galactosemia based on genome wide association studies, epigenetic factors, transcript regulation, post-translational genetic modifications and biomarker discovery through metabolomic studies. We will delve into the current approaches being undertaken to analyze metadata using bioinformatic approaches and the emerging interventions using genome editing platforms as applied to animal models.

Carrageenan From (Rhodophyta, Solieriaceae): Metabolism, Structure, Production, and Application.

Carrageenan is a polysaccharide derived from red algae (seaweed) with enormous economic potential in a wide range of industries, including pharmaceuticals, food, cosmetics, printing, and textiles. Carrageenan is primarily produced through aquaculture-based seaweed farming, with and species accounting for more than 90% of global output. There are three major types of carrageenan found in red algae: kappa ()-, iota ()-, and lambda ()-carrageenan.

Suppression of Oxidative Stress and Proinflammatory Cytokines Is a Potential Therapeutic Action of B. (Moraceae) against Carbon Tetrachloride (CCl)-Induced Hepatotoxicity in Rats.

Local tribes use the leaves of B. (Moraceae), a traditional Malaysian medicine, as a vegetable dish, a tonic, and to treat ailments including fever, jaundice and ringworm. The purpose of this study was to look into the possible therapeutic effects of leaf extract against carbon tetrachloride (CCl)-induced liver damage in rats.

Production of Lectins from Marine Algae: Current Status, Challenges, and Opportunities for Non-Destructive Extraction.

Marine algae are an excellent source of novel lectins. The isolation of lectins from marine algae expands the diversity in structure and carbohydrate specificities of lectins isolated from other sources. Marine algal lectins have been reported to have antiviral, antitumor, and antibacterial activity.

Dataset of genome sequence, assembly, and functional annotation of sp. (PBVC088), a marine bacterium associated with the toxin-producing harmful dinoflagellate, var. .

The dataset comprises a whole-genome sequence of sp. PBVC088, a symbiotic (Gram-negative) bacterium associated with var. c, which has been associated with harmful algal blooms in the coastal waters of west Sabah, Malaysia.

Dataset of 16S ribosomal DNA sequences of bacteria isolated from marine red algae .

The data provided in the article contains bacterial community profiles present on the surface of red algae () isolated directly after collection and after 30 days of cultivation in a closed circulation system. The explants of were cultivated in a laboratory setting under controlled growth conditions for 30 days in order to determine bacteria that could adapt to controlled culture conditions. Amplification and sequencing of bacterial 16S rDNA amplicon were performed on bacterial isolates associated with the seedlings.

Infectious Bronchitis Virus (Gammacoronavirus) in Poultry Farming: Vaccination, Immune Response and Measures for Mitigation.

Infectious bronchitis virus (IBV) poses significant financial and biosecurity challenges to the commercial poultry farming industry. IBV is the causative agent of multi-systemic infection in the respiratory, reproductive and renal systems, which is similar to the symptoms of various viral and bacterial diseases reported in chickens. The avian immune system manifests the ability to respond to subsequent exposure with an antigen by stimulating mucosal, humoral and cell-mediated immunity.

A Concise Review of and Related Bamboos: Germplasm Conservation, Propagation and Molecular Biology.

Bamboos represent an emerging forest resource of economic significance and provide an avenue for sustainable development of forest resources. The development of the commercial bamboo industry is founded upon efficient molecular and technical approaches for the selection and rapid multiplication of elite germplasm for its subsequent propagation via commercial agro-forestry business enterprises. This review will delve into the micropropagation of , one of the most widely cultivated commercial varieties of bamboo, and will encompass the selection of germplasm, establishment of explants in vitro and micropropagation techniques.

A mini-review on the impact of COVID 19 on vital organs.

COVID-19 (Corona Virus Disease-2019) is an infectious disease caused by a novel coronavirus, known as the acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is a highly contagious disease that has already affected more than 220 countries globally, infecting more than 212 million people and resulting in the death of over 4.4 million people.

Comparative Transcriptome Profiling of (Rhodophyta, Solieriaceae) in Response to Light of Different Wavelengths and Carbon Dioxide Enrichment.

Rhodophyta (red algae) comprises over 6000 species, however, there have only been a few comparative transcriptomic studies due to their under-representation in genomic databases. , a Gigartinales algae, is a valuable source of carrageenan and is extensively cultivated in many countries. The majority of seaweed farming in Southeast Asia is done in intertidal zones under varying light (i.

Genomic data of two and two strains isolated from the acid mine drainage site at Mamut Copper Mine, Ranau, Malaysia.

The genomic data of four bacteria strains isolated from the abandoned Mamut Copper Mine, an Acid Mine Drainage (AMD) site is presented in this report. Two of these strains belong to the genus , while the other two belong to the genus The draft genome size of sp. strain MCMY3 was 6,396,595 bp (GC: 63.

Metagenomic data of bacterial community from different land uses at the river basin, Kelantan.

The data provided in the article includes the sequence of bacterial 16S rRNA gene from a high conservation value forest, logged forest, rubber plantation and oil palm plantation collected at Kelantan river basin. The logged forest area was previously notified as a flooding region. The total gDNA of bacterial community was amplified via polymerase chain reaction at V3-V4 regions using a pair of specific universal primer.

Draft genome sequence data of two bacteria from serogroup C type.

is a gram-negative rod-shape bacterium from the family of that can cause a wide range of human disease such as enteric fever, gastroenteritis and bacteremia. Here we sequenced two genomes of bacteria isolated from the host. Genomic DNA of the two isolates were extracted and subjected to whole genome sequencing using Illumina platform.

Draft Genome Sequence of a Phytopathogenic Ganoderma sp. Strain That Causes Basal Stem Rot Disease on Oil Palm in Sabah, Malaysia.

Basal stem rot (BSR) disease on is known to be caused by members of the pathogenic fungal genus , especially the species This species affects oil palm plantation in Sabah, Malaysia. The genome sequence (52.28 Mbp) will add to the representation of this genus, especially in regard to BSR disease.

Complete mitochondrial genome of six (Napoleon Wrasse): an endangered marine fish species from Sabah, Malaysia.

We report here the complete mitochondrial (mt) genomes of six individuals of (Napoleon Wrasse), an endangered marine fish species. The six mt DNA sequences had an average size of 17,000 kb and encoded 22 tRNA, two sRNA, 13 highly conserved protein coding genes and a control region. The polymorphic variation (control region) in these six individuals suggests their potential use as a specific marker for phylogeographic conservation.

Inhibition and Substrate Specificity Properties of FKBP22 from a Psychrotrophic Bacterium, Shewanella sp. SIB1.

SIB1 FKBP22 is a peptidyl prolyl cis-trans isomerase (PPIase) member from a psychrotrophic bacterium, Shewanella sp. SIB1, consisting of N- and C-domains responsible for dimerization and catalytic PPIase activity, respectively. This protein was assumed to be involved in cold adaptation of SIB1 cells through its dual activity of PPIase activity and chaperone like-function.

Adaptive Strategies of Isolated from Acid Mine Drainage Site in Sabah, Malaysia.

The adaptive process in bacteria is driven by specific genetic elements which regulate phenotypic characteristics such as tolerance to high metal ion concentrations and the secretion of protective biofilms. Extreme environments such as those associated with heavy metal pollution and extremes of acidity offer opportunities to study the adaptive mechanisms of microorganisms. This study focused on the genome analysis of (Bt MCMY1), a gram positive rod shaped bacterium isolated from an acid mine drainage site in Sabah, Malaysia by using a combination of Single Molecule Real Time DNA Sequencing, Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR).

Extensive sharing of mitochondrial COI and CYB haplotypes among reef-building staghorn corals (Acropora spp.) in Sabah, North Borneo.

This study is aimed at establishing a baseline on the genetic diversity of the Acropora corals of Sabah, North Borneo based on variations in the partial COI and CYB nucleotide sequences. Comparison across 50 shallow-water Acropora morphospecies indicated that the low substitution rates in the two genes were due to negative selection and that rate heterogeneity between them was asymmetric. CYB appeared to have evolved faster than COI in the Acropora as indicated by differences in the rate of pairwise genetic distance, degrees of transition bias (T/T), synonymous-to-nonsynonymous rate ratio (d/d), and substitution patterns at the three codon positions.