A Process-Based Standardization of an Intraoperative Escalation Protocol in Anesthesiology.

Prompt recognition and management of critical events is pivotal for the provision of safe anesthetic care. This requires a well-functioning team that focuses on effective communication, timely decision-making, and escalation of potential complications. We believe that variation in bedside care leads to "near-misses," adverse outcomes, and serious safety events (SSEs).

Mortality and costs associated with acute kidney injury following major elective, non-cardiac surgery.

Objective: This study evaluated postoperative AKI severity and its relation to short- and long-term patient outcomes.

Design: A retrospective, single-center cohort study of patients undergoing surgery from January 2015 to May 2020.

Setting: An urban, academic medical center.

Early tracheostomy: on the cutting edge, some benefit more than others.

Purpose Of Review: The decision to undergo early tracheostomy in critically ill patients has been the subject of multiple studies in recent years, including several meta-analyses and a large-scale examination of the National in-patient Sampling (NIS) database. The research has focused on different patient populations, and identified common outcomes measures related to ventilation. At the crux of the new research is the decision to undergo an additional invasive procedure, mainly tracheostomy, rather than attempt endotracheal tube ventilation with or without early extubation.

Donation after circulatory death: opportunities on the horizon.

Purpose Of Review: Organ transplantation remains the gold standard therapy for many end-organ diseases. The demand for donor organs continues to grow to far exceed supply. This review summarizes recent protocols, procedures, and ethics surrounding the increased utilization of donors after circulatory death for transplantation.

Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature.

Purpose Of Review: Postoperative cognitive dysfunction (POCD) occurs in 20-50% of postsurgical patients with a higher prevalence in elderly patients and patients with vascular disease and heart failure. In addition, POCD has been associated with many negative outcomes, such as increased hospital length of stay, increased rates of institutionalization, and higher patient mortality. This brief review discusses select evidence suggesting an association between neuroinflammation and POCD and whether the use of dexmedetomidine, a short-acting alpha 2 agonist, may ameliorate the incidence of POCD.

A systematic method for simulating total ionizing dose effects using the finite elements method.

Simulation of total ionizing dose effects in field isolation of FET technologies requires transport mechanisms in the oxide to be considered. In this work, carrier transport and trapping in thick oxides using the finite elements method in the Synopsys Sentaurus platform are systematically simulated. Carriers are generated in the oxide and are transported out through a direct contact with the gate and thermionic emission to the silicon.

Implications of claimant-favorable approaches used in dose and probability of causation calculations under EEOICPA.

There are many claimant-favorable factors inherent in both the reconstruction of radiation dose and the calculation of probability of causation under Part B of the Energy Employees Occupational Illness Compensation Program Act of 2000. These factors result in an approximate 30% compensation rate for claims filed under EEOICPA, which is roughly an order of magnitude greater than the likely incidence of increased cancers as predicted by epidemiology studies and risk models. Additionally, there is essentially no chance that a claim that is denied compensation actually involves a radiation-induced cancer.