An Underappreciated Cytomorphological Feature of Secretory Carcinoma of Salivary Gland on Fine Needle Aspiration Biopsy: Case Report with Literature Review.

Secretory carcinoma (SC) of salivary gland, previously known as mammary analogue secretory carcinoma, is a rare low-grade malignancy harboring a diagnostic ETV6-NTRK3 gene fusion. SC of salivary gland shares histopathological, immunohistochemical and genetic characteristics with SC of the breast. There are several previous cytomorphological characterizations of SC of salivary gland reported in the literature.

Acral myxoinflammatory fibroblastic sarcoma fine needle aspiration: a case report.

Cytological diagnosis of low grade sarcomas can be a daunting task, owing to the varied cytomorphological appearances possible. We report a case of acral myxoinflammatory fibroblastic sarcoma (AMIFS) in a woman who presented with a longstanding mass on the dorsum of her left foot. The diagnosis was suggested by fine needle aspiration cytology and established by wide excision.

Clinical experience with the Cervista HPV HR assay: correlation of cytology and HPV status from 56,501 specimens.

Testing for high-risk (HR) human papillomavirus (HPV) is a key component of current recommendations for cervical cancer screening. Herein is described our clinical experience using Cervista HPV HR, a testing platform recently approved by the US Food and Drug Administration for clinical use. Using data from a high-volume commercial laboratory, a retrospective analysis of cytologic and Cervista HPV HR test results from 56,501 samples was performed, and an indirect comparison was made with previous experience with 53,008 samples tested using the Hybrid Capture 2 platform.

Thyroid carcinoma showing thymus-like differentiation (CASTLE): case report with cytomorphology and review of the literature.

Thyroid carcinoma showing thymus-like differentiation (CASTLE) is a rare tumor of the thyroid gland or adjacent soft tissues of the neck. Given the comparatively good prognosis of CASTLE, it is crucial to distinguish this neoplasm from other more aggressive thyroid neoplasms that can have similar or overlapping cytomorphological features. However, there is little information about the cytomorphology of CASTLE available in the literature.

Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma.

Cell surface expression of glucose-regulated protein 78 (GRP78) occurs in several types of cancer; however, its role in the behavior of primary cutaneous melanoma is not well studied. The association of cell surface GRP78 with other proteins such as MTJ1 stimulates cell proliferation. In this study, we characterized the pattern of expression of GRP78 and MTJ1 in invasive primary cutaneous melanomas and analyzed the relationships between the pattern of expression and various clinicopathological parameters.

Extranodal follicular dendritic cell sarcoma.

Extranodal follicular dendritic cell sarcoma is a rare tumor of follicular dendritic cells that can occur in a wide variety of sites. Although fairly well characterized histologically, with a distinct immunophenotype, it remains under-recognized, with as many as one third of cases initially misdiagnosed. This is often due to a failure to consider the entity.

Hybrid neurofibroma-schwannoma of the orbit.

Purpose: To report a case of an unusual orbital tumor with histologic features of both neurofibroma and schwannoma.

Methods: Clinical and pathological findings are presented in a patient with an orbital tumor.

Results: Orbital magnetic resonance imaging in a 51-year-old female revealed a heterogeneously enhancing right orbital mass.

Kaposi sarcoma after bilateral lung transplantation.

We describe radiologic findings in 2 patients and 18-fluoro-deoxy-glucose positron emission tomography/computed tomography findings in 1 patient who developed Kaposi sarcoma of the lung after bilateral lung transplantation. These findings included lung nodules, mediastinal or hilar lymphadenopathy, and pleural fluid.