Publications by authors named "Kenneth C Y Yu"
Objective: To report and discuss the outcome of a prospective, internally controlled, randomized, double-blind, split-face study comparing the onset of action of 2 commercially available botulinum neuromodulators.
Methods: Ninety individuals with moderate-to-severe lateral orbital rhytids were treated with onabotulinumtoxinA, 10 U, and abobotulinumtoxinA, 30 U, for the treatment of lateral orbital rhytids. Participants were assessed live with a validated 5-point photographic scale before treatment and on days 2, 4, and 6 after treatment.
Objective: To compare 2 commercially available botulinum neuromodulators in a randomized, double-blind, split-face study.
Methods: Ninety patients were treated with 10 U of onabotulinumtoxinA and 30 U of abobotulinumtoxinA for the treatment of lateral orbital rhytids. Patients were assessed live with a validated 5-point photographic scale prior to treatment and at 30 days.
Effect of SOD1 overexpression on age- and noise-related hearing loss.
Free Radic Biol Med
April 2003
Article Synopsis
- Reactive oxygen species (ROS) are linked to hearing loss caused by aging and noise exposure, with superoxide dismutases (SODs) acting as a defense against ROS damage.
- The absence of the Cu/Zn SOD (SOD1) worsens hearing loss from noise and aging, while overexpressing SOD1 was thought to protect against these losses.
- However, research using transgenic mice with the human SOD1 gene found no protective effects against age-related or noise-induced hearing loss, suggesting that oxidative metabolism in the cochlea is more complex than previously thought.