Rapid implementation of a clinical decision-support workflow during the national blood culture bottle shortage.

Background: The United States Food and Drug Administration recently announced a national blood culture (BC) bottle shortage; the exact date of restoration is still being determined.

Aim: Implement a workflow to mitigate the BC bottle shortage at our hospital.

Methods: We created the following clinical decision support workflow in electronic medical record to help mitigate BC bottle use: (a) limit to two BC in 24 hours, (b) only repeat BC if 72 hours have passed from the prior sets, (c) do not repeat BC for coagulase-negative bacteremia when considered a contaminant (i.