Novel Image-Guided Percutaneous Lung Tissue Excision Device With Integrated Sealing of Blood Vessels and Airways: An In Vivo Preclinical Study.

Objective: This study evaluated the efficacy of the Minimally Invasive Targeted Resection (MiTR) device, a novel electrosurgical instrument that allows for targeted excision of a lung abnormality while using bipolar radiofrequency (RF) energy to seal blood vessels and airways.

Methods: The MiTR system was evaluated in 7 acute and 2 chronic porcine (7-day) models to evaluate the efficacy of tissue excision with bipolar RF sealing of blood vessels and airways and application of an autologous blood patch into the excised tissue cavity. Air leak was recorded for all evaluations.

Safety and Accuracy of a Novel Bioimpedance System for Real-Time Detection and Monitoring of Endovascular Procedure-Related Bleeding in a Porcine Model.

Objectives: The aim of this study was to determine the safety and accuracy of a novel bleed detection system, the Early Bird Bleed Monitoring System (EBBMS; Saranas) for the detection of simulated internal bleeding and the monitoring of bleed progression associated with endovascular procedures.

Background: Periprocedural bleeding events during endovascular procedures are frequent and are associated with increased morbidity, mortality, and healthcare costs.

Methods: This study was a prospective, self-controlled, acute animal study including 20 Yorkshire cross swine undergoing endovascular procedures involving cannulation of both femoral artery and vein.