Publications by authors named "Kennedy Spann"
Background: Dexamethasone is routinely administered to horses but its effect on the antibody response to a commercial EIV/EHV vaccine is unclear.
Hypothesis: Horses receiving dexamethasone will have lower postvaccination antibody levels against EIV and EHV-1 than vaccinated controls.
Animals: Fifty-five healthy adult research horses.
Article Synopsis
- EHV-1 vaccines are typically given intranasally during outbreaks, but their effectiveness and the complications in diagnosing EHV-1 infections post-vaccination are not well understood.
- This study aimed to evaluate the systemic antibody response from two types of EHV-1 vaccines (Calvenza and Rhinomune) and how long the virus could be detected in nasal secretions after vaccination.
- Results showed no significant immune response in vaccinated horses, but a high incidence of detectable vaccine-derived EHV-1 in nasal secretions, which could complicate diagnosis during outbreaks.
While some companion animals have been shown to be susceptible to SARS-CoV-2, their role in the COVID-19 pandemic has remained poorly investigated. Equids are susceptible to SARS-CoV-2 based on the similarity of the human ACE-2 receptor and reports of infection. Clinical disease and prevalence factors associated with SARS-CoV-2 infection in equids have not yet been investigated.
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