Publications by authors named "Kenji Minari"
Article Synopsis
- - A new cell line called qMDCK-Cs was developed to isolate viruses for seasonal influenza vaccines, achieving over 70% efficiency when tested with clinical samples from influenza-positive patients.
- - The isolated strains showed strong antigenic similarity to current vaccines, with 100% of some strains (like A/H1N1pdm09) matching criteria set by the World Health Organization for effectiveness.
- - This method reduces the need for seasonal clinical sample collection and analysis, making it a more efficient approach for developing appropriate vaccine viruses.
Background: Wild ducks are the natural hosts of influenza A viruses. Duck influenza, therefore, has been believed inapparent infection with influenza A viruses, including highly pathogenic avian influenza viruses (HPAIVs) in chickens. In fact, ducks experimentally infected with an HPAIV strain, A/Hong Kong/483/1997 (H5N1) (HK483), did not show any clinical signs.
View Article and Find Full Text PDFH5 and H7 highly pathogenic avian influenza virus (HPAIV) represent a major global concern in poultries and human health. Avian influenza (AI) vaccines are available but not preferred for field applications, primarily because vaccination interferes with sero-surveillances of AIV infection. To overcome the problem, ELISA systems using non-structural protein 1 (NS1) of AIV as antigens (NS1-ELISA) have been developed to measure anti-NS1 antibodies that are raised in AIV-infected but not in vaccinated chickens.
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