Effectiveness of multiple-dose activated charcoal in lamotrigine poisoning: a case series.

Introduction: Lamotrigine toxicity can cause coma, seizures, and intraventricular conduction disturbances, and treatment options include good supportive care. We report two cases of lamotrigine poisoning in which multiple-dose activated charcoal may have shortened the elimination half-life of lamotrigine.

Case 1: A 21-year-old woman ingested 15.

Wireless biosensor system for real-time L-lactic acid monitoring in fish.

We have developed a wireless biosensor system to continuously monitor L-lactic acid concentrations in fish. The blood L-lactic acid level of fish is a barometer of stress. The biosensor comprised Pt-Ir wire (φ0.

Association between affective temperaments and brain-derived neurotrophic factor, glycogen synthase kinase 3β and Wnt signaling pathway gene polymorphisms in healthy subjects.

Background: There is increased attention towards elucidating genetic factors that underlie both psychiatric diseases as well as healthy psychological phenomena. Recent evidence suggests that temperamental traits, including affective temperaments, are heritable and associated with genetic polymorphisms. Genetic research examining affective temperaments using the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A) may therefore elucidate the concept of a spectrum of mood disorders and the genetic relationship between affective temperaments and mood disorders.