A retrospective analysis of factors associated with deep contraceptive implant removals compared to superficial removals.

Objective: To identify factors associated with the need for a deep etonogestrel contraceptive implant removal as compared to superficial removal.

Study Design: We conducted a retrospective cohort study of patients undergoing contraceptive implant removal from January 2014 to January 2023. We extracted key patient characteristics from electronic health record review and compared patients requiring deep removal versus routine superficial removal using Chi-squared, Fischer's exact, and Mann-Whitney U test.

Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones.

spp. are "nature's antibiotic factories" that produce valuable bioactive metabolites, such as the cytotoxic anthracycline polyketides. While the anthracyclines have hundreds of natural and chemically synthesized analogues, much of the chemical diversity stems from enzymatic modifications to the saccharide chains and, to a lesser extent, from alterations to the core scaffold.

Complications of second trimester induction for abortion or fetal demise for patients with and without prior cesarean delivery.

Objective: Compare complication rates of second trimester induction for abortion or fetal demise for patients with and without prior cesarean delivery.

Study Design: Retrospective cohort study examining induction for abortion or fetal demise for pregnancies from 14w0d to 23w6d gestation at 2 urban academic medical centers from 2009 to 2019. Exclusion criteria included preterm labor or cervical insufficiency, neonatal interventions, or if misoprostol was not the primary induction method.