Publications by authors named "Kenari A"
Plasma extracellular vesicles and particles (EVPs) are enriched in biomolecules that reflect individuals' physiological and pathological states. Several studies have demonstrated the potential of human plasma EVPs as a novel liquid biopsy. Here we describe a protocol for human plasma EVPs isolation and proteomic characterization.
View Article and Find Full Text PDFCervical cancer is one of the important cancers in women. Research on novel treatment approach can reduce the mortality and burden. Although radiotherapy is a common treatment, its negative side effects have concerned physician.
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- Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease marked by misfolded proteins affecting motor neurons, and this study focuses on the role of small extracellular vesicles (exosomes) in this process.
- Researchers isolated motor cortex extracellular vesicles (MCEVs) from ALS patients and neurological controls, identifying a panel of 16 proteins that are significantly altered in ALS.
- Among these proteins, several RNA-binding proteins related to stress granules were found, suggesting a connection between stress granule dynamics and the disease, highlighting exosomes as potential biomarkers for ALS.
Background: Our aim of this study was to evaluate the possible association between homocysteine levels and Buerger's disease in a case-control study.
Methods: 25 patients with Buerger's disease based on Shionoya's clinical criteria, and 25 heavy smokers along with 25 healthy non-smokers (control) were recruited for this study. All groups were matched for age.
Aim: Spasm of the internal anal sphincter plays a role in haemorrhoidal disease and may be a source of anal pain after haemorrhoid surgery. In this study, we investigated the effect of topical diltiazem (DTZ) on postoperative pain following Milligan-Morgan haemorrhoidectomy.
Method: After haemorrhoidectomy, 33 patients were randomly assigned to receive DTZ ointment (2%; n = 16) or a placebo ointment (n = 17).
Background: Splenic preservation following trauma has been decisively established as the preferred, safe and feasible therapeutic modality.
Objective: To evaluate the outcomes of non-operative management in adults with blunt splenic injuries and determine the predictive factors of failure.
Methods: Patients admitted to a tertiary trauma centre with blunt splenic trauma during a 10 year period were studied retrospectively.