Small Peptides from Periplaneta americana Inhibits Oxidative Stress-Induced KGN Cell Apoptosis by Regulating Mitochondrial Function Through Bcl2L13.

This study examined the protective effects of small peptides from Periplaneta americana against HO-induced mitochondrial injury in human ovarian granulosa cells. The ATP level and mitochondrial membrane potential as well as the quantity and ultrastructure of mitochondria in cells were detected. Mitochondrial DNA copy number and expression levels of Bcl2L13, LC3B, and p62 were tested.

Signaling pathways of Periplaneta americana peptide resist HO-induced apoptosis in pig-ovary granulosa cells through FoxO1.

Granulosa cell apoptosis induced by oxidative stress is an important cause of follicular atresia. Our previous studies found that Periplaneta americana peptide (PAP) decreased HO-induced apoptosis of pig-ovary granulosa cells (PGCs) through FoxO1. The aim of this study is to investigate the signaling pathways involved in PAP resistance against HO-induced apoptosis of PGCs.

Protective effect of small peptides from Periplaneta americana on cyclophosphamide-induced premature ovarian failure.

Aim: To investigate the protective effect of small peptides from Periplaneta americana (SPPA) on cyclophosphamide (CP)-induced premature ovarian failure (POF) in mice. Silent mating type information regulation 2 homolog 1 (SIRT1) /tumor-associated protein 53 (p53) signaling pathway plays an important role in delaying POF. Hematopoietic progenitor cell antigen (CD34) reflects ovarian aging from the side.

Mechanism of action and the uses betaine in pig production.

Betaine, the trimethyl derivative of glycine, is a good methyl group donor, and an important component in pig production. However, betaine has not been extensively studied in this field. Therefore, in this study, we reviewed the effects of betaine in pig production performance, meat quality and reproductive performance, as well as its mechanisms, to provide a theoretical basis for the optimal use and development of this compound.

Periplaneta americana peptide decreases apoptosis of pig-ovary granulosa cells induced by H O through FoxO1.

Oxidative stress can induce apoptosis of granulosa cells and lead to follicular atresia, thereby reducing the number of pigs giving birth. The aim of this study was to investigate the protective effect of Periplaneta americana peptide (PAP) on the apoptosis of the granulosa cells of pig ovaries (PGCs) induced by hydrogen peroxide (H O ) via FoxO1. PGCs were treated with H O to establish a cell apoptosis model.

The protective effect of small peptides from Periplaneta americana on hydrogen peroxide-induced apoptosis of granular cells.

This study investigates the protective effect of small peptides from Periplaneta americana (SPPA) on hydrogen peroxide (HO)-induced apoptosis of ovarian granular cells. HO was applied to human ovarian granular cells (KGN cell strains). Cell viability was tested by cell counting Kit-8 (CCK-8).

Copper oxide nanoparticles alter cellular morphology via disturbing the actin cytoskeleton dynamics in roots.

Copper oxide nanoparticles (CuO NPs) have severe nano-toxic effects on organisms. Limited data is available on influence of CuO NPs on plant cells. Here, the molecular mechanisms involved in the toxicity of CuO NPs are studied.

Reliability and validity of the Chinese pediatric voice handicap index.

Objectives: To evaluate the reliability and validity of the Chinese version of pediatric voice handicap index (pVHI).

Material And Methods: The original English version-pVHI was translated into Chinese. Parents of 52 children with voice dysphonia and 43 children with no history or symptoms of voice problems were asked to fill the Chinese pVHI questionnaires twice with an interval of 2 weeks.

Survival in Vivo Canine Phonation Model Without Stimulation.

Objectives: We describe a survival nonstimulated in vivo canine phonation model using distending laryngoscope, cramp frame, and constant humidified glottal airflow to elicit phonation.

Methods: Five beagle dogs were involved in this study. One cuffed endotracheal tube was placed below the glottis through the tracheotomy and delivered humidified airflow to the glottis.