Publications by authors named "Kemeng Liu"

Since agriculture is a major source of greenhouse gas emissions, accurately calculating these emissions is essential for simultaneously addressing climate change and food security challenges. This paper explores the critical role of trade in transferring agricultural greenhouse gas (AGHG) emissions throughout global agricultural supply chains. We develop a detailed AGHG emission inventory with comprehensive coverage across a wide range of countries and emission sources at first.

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Brucellosis, caused by the intracellular pathogen , is a major zoonotic infection that promotes reproductive disease in domestic animals and chronic debilitating conditions in humans. The ArsR family of transcriptional regulators plays key roles in diverse cellular processes, including metal ion homeostasis, responding to adverse conditions, and virulence. However, little is known about the function of ArsR family members in .

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ENG/CD105 encodes a vascular endothelial glycoprotein and plays a crucial role in modulating angiogenesis. However, the significance of ENG expression, DNA methylation, immuno-response, and cordycepin (CD) regulation as diagnostic, prognostic, and therapeutic markers for breast invasive carcinoma (BRCA) remains unclear. As a result, ENG is decreased in BRCA tissues compared with corresponding healthy tissues.

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Article Synopsis
  • The study investigates the effectiveness of the "schisandra-evodia" herb pair in treating Alzheimer's disease (AD) in rats through pharmacodynamic assessments and metabolomic analyses.
  • Results indicated that S-E significantly improved long-term memory, spatial learning, and reduced cognitive impairment associated with Aβ in AD rats, while also enhancing neuron structure and reducing inflammation.
  • Metabolomic analysis of serum and urine revealed changes in 40 serum and 38 urine metabolites, highlighting the impact of S-E on various metabolic pathways related to brain health, which could inform future clinical applications.
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Hereditary hemorrhagic telangiectasia (HHT), also called Rendu-Osler syndrome, is a group of rare genetic diseases characterized by autosomal dominance, multisystemic vascular dysplasia, and age-related penetrance. This includes arteriovenous malformations (AVMs) in the skin, brain, lung, liver, and mucous membranes. The correlations between the phenotype and genotype for HHT are not clear.

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Unlabelled: and are traditional Chinese herbs used to treat neurodegenerative diseases. This study investigates the combined effects of SC and ER on learning and memory in an Alzheimer's disease rat model and their underlying mechanisms.

Methods: High-performance liquid chromatography was employed to analyze the primary active constituents of Schisandra and Evodia.

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This study aims to investigate the protective effect and mechanism of herb pair (DKHP) on ischemic heart disease (IHD). The rat model of myocardial reperfusion injury (MIRI) was established by ligation of the left anterior descending coronary artery. Rats were randomly divided into seven groups and administered orally for 7 days: control group, IHD group, DKHP1:1 group, DKHP1:2 group, DKHP2:1 group, DKHP1:3 group, DKHP3:1 group, the dosage was 2.

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Tetrahydroprotoberberines (THPBs) are plant-specific alkaloids with significant medicinal value. They are present in trace amounts in plants and are difficult to chemically synthesize due to stereoselectivity and an unfavorable environment. In this study, a selective methylation strategy was developed for the biocatalysis of seven high-value-added THPB compounds using 4'--methyltransferase (), norcoclaurine 6--methyltransferase (), and ()-scoulerine 9--methyltransferase ( and ) in engineered .

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Nitrous oxide (NO) is the third most potent greenhouse gas (GHG) and the most important ozone depleting substance. But how global NO emissions are connected through the interwoven trade network remains unclear. This paper attempts to specifically trace anthropogenic NO emissions via global trade networks using a multi-regional input-output model and a complex network model.

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Article Synopsis
  • Therapeutic monoclonal antibodies possess complex structures and functions, and their manufacturing processes are often proprietary, necessitating a thorough similarity assessment for proposed biosimilars against a reference product (RP).
  • A detailed analytical comparison involving a tier-based quality attribute evaluation was conducted between HLX04 (a proposed biosimilar) and two reference Avastin products sourced from China and Europe, highlighting HLX04's strong similarity in physicochemical properties and biological activities.
  • The study noted minor differences in certain binding activities and glycosylation but confirmed that these differences do not negatively affect clinical outcomes, supporting the conclusion that HLX04 is comparable to both CN-Avastin and EU-Av
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Acute myocardial infarction (AMI) is a threat to human life and physical health worldwide. Timely reperfusion is very important to limit infarct size and protect ischemic myocardium. Unfortunately, it has also caused severer myocardial damage, which is called "myocardial ischemia/ reperfusion injury (MIRI)".

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Continuous monoculture of cool-season turfgrass causes soil degradation, and visual turf quality decline is a major concern in black soil regions of Northeast China. Turf mixtures can enhance turfgrass resistance to biotic and abiotic stresses and increase soil microbial diversity. Understanding mechanism by plant-soil interactions and changes of black soil microbial communities in turf mixture is beneficial to restoring the degradation of urbanized black soils and maintaining sustainable development of urban landscape ecology.

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