Publications by authors named "Kelvin Roland Mubiru"

Article Synopsis
  • - Prostate cancer is a major health issue globally, particularly in resource-limited settings like Uganda, where late-stage diagnosis contributes to high mortality rates.
  • - A study at the Uganda Cancer Institute reviewed 300 patients with metastatic prostate cancer (mPCa) over five years, finding a significant drop in overall survival from 92.4% at one year to 45.2% at five years, with factors like high Gleason scores and fewer chemotherapy cycles linked to poorer outcomes.
  • - Most patients experienced severe lower urinary tract symptoms and a high median prostate-specific antigen (PSA) level at diagnosis, indicating advanced disease, emphasizing the need for improved early detection and treatment strategies in such settings.
View Article and Find Full Text PDF

Background: In 2016, Uganda added Hydroxyurea (HU) to the list of essential drugs to treat sickle cell disease SCD. However, Hydroxyurea utilization has been low for several countries in sub-Saharan Africa. This study examined patient-related barriers to hydroxyurea use among adolescent and adult patients with sickle cell disease in Mulago and Kiruddu hospitals, in Uganda.

View Article and Find Full Text PDF

Purpose: Acute leukemias are associated with substantial morbidity and mortality, particularly in the adult population. Despite an increasing burden of acute leukemia in developing countries, there are limited data on clinical outcomes and prognostic factors in this setting. In this study, we aimed to describe the clinical characteristics, survival, and prognostic factors of adults with acute leukemia at the Uganda Cancer Institute (UCI).

View Article and Find Full Text PDF